Results 191 to 200 of about 688,262 (355)

Clinical Tumor Sequencing: An Incidental Casualty of the American College of Medical Genetics and Genomics Recommendations for Reporting of Incidental Findings

, 2014
D. Williams Parsons, Angshumoy Roy, Sharon E. Plon, Sameek Roychowdhury, Arul M. Chinnaiyan   +4 more
openalex   +2 more sources

Clinical features and genetics in non-5q spinal muscular atrophy caused by acid ceramidase deficiency

, 2021
Mihaela Axente, Elena-Silvia Shelby, Andrada Mirea, Corina Sporea, Mihaela Badina, Liliana Pădure, Daniela Adriana Ion   +6 more
openalex   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Rhabdoid Tumor Predisposition Syndrome : A Comprehensive Review of Genetics, Clinical Manifestations, and Management. [PDF]

J Korean Neurosurg Soc
Kim T, Phi JH.
europepmc   +1 more source

Molecular genetics of MARVELD2 and clinical phenotype in Pakistani and Slovak families segregating DFNB49 hearing loss

, 2015
Gowri Nayak, Lukáš Varga, Claire E. Trincot, Mohsin Shahzad, Penelope L. Friedman, I Klimeś, John H. Greinwald, Sheikh Riazuddin, Ivica Mašindová, Milan Profant, Shaheen N. Khan, Thomas B. Friedman, Zubair M. Ahmed, Daniela Gašperíková, Sheikh Riazuddin, Saima Riazuddin   +15 more
openalex   +2 more sources

A Case Based Approach to Clinical Genetics of Thoracic Aortic Aneurysm/Dissection [PDF]

, 2016
Betti Giusti, Stefano Nistri, Elena Sticchi, Rosina De Cario, Rosanna Abbate, Gian Franco Gensini, Guglielmina Pepe   +6 more
openalex   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Correction: Marszałek-Kruk et al. Treacher Collins Syndrome: Genetics, Clinical Features and Management. <i>Genes</i> 2021, <i>12</i>, 1392. [PDF]

Genes (Basel)
Marszałek-Kruk BA, Wójcicki P, Dowgierd K, Śmigiel R.   +3 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Von Hippel-Lindau Disease : A Comprehensive Review of Diagnosis, Genetics, Clinical Challenges, and Surveillance. [PDF]

J Korean Neurosurg Soc
Jung NY, Park JB.
europepmc   +1 more source