Results 221 to 230 of about 10,831,444 (295)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Implementing mainstream germline genetic testing in breast cancer across Europe. [PDF]

BJC Rep
Pérez-Ballestero E, Shire SA, Krajc M, Irmejs A, Foretová L, Frank S, Kahre T, van Overeem Hansen T, Koppert L, Burgemeister AL, Tischkowitz M, Balmaña J, Bajalica-Lagercrantz S, ERN GENTURIS.   +13 more
europepmc   +1 more source

Quality improvement initiative to optimize use of rapid genomic sequencing in a level IV NICU. [PDF]

J Perinatol
D'Gama AM, Hu RS, Del Rosario MC, Hills S, Park HJ, Mehra AT, Tannenbaum LS, Morton SU, Agrawal PB, Wojcik MH.   +9 more
europepmc   +1 more source

Prolonged Intrahepatic Cholestasis After Acute Hepatitis E Infection: A Case Series and Genetic Analysis. [PDF]

J Viral Hepat
Fraga M, Kasmi S, Weber SN, Liebe R, Sempoux C, Saadat A, Fellay J, Kenngott-Kelber S, Zimmer V, Lammert F, Krawczyk M, Jüngst C.   +11 more
europepmc   +1 more source

Genetics of CAKUT. [PDF]

Med Genet
Hilger AC, Westland R, Hoefele J.
europepmc   +1 more source

Ethical and clinical challenges in managing low-penetrance CNVs: insights from Portuguese clinical geneticists. [PDF]

Front Genet
Soares AR, Da Silva JD, Caldas Afonso A, Carvalho AS.   +3 more
europepmc   +1 more source

Meeting abstracts from the Annual Conference "Clinical Genetics of Cancer 2024". [PDF]

Hered Cancer Clin Pract
europepmc   +1 more source