Results 241 to 250 of about 1,217,828 (289)

Clinical variants of acrodermatitis enteropathica and its co-relation with genetics

, 2016
Sarabjit Kaur, Ankita Sangwan, Priyadarshini Sahu, Surabhi Dayal, VijayKumar Jain   +4 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A recurrent mosaic mutation in SMO, encoding the hedgehog signal transducer smoothened, is the major cause of Curry-Jones syndrome [PDF]

, 2016
et al,, Grange, Dorothy K
core   +1 more source

Clinical mitochondrial genetics

, 1999
Patrick F. Chinnery, Neil Howell, Richard M. Andrews, Douglass M. Turnbull   +3 more
openalex   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Preparedness for working with genomic medicine among Swedish non-genetics physicians - a nation-wide survey study. [PDF]

J Community Genet
Björk J, Friedman M, Nisselle A, Malmgren CI, Soller MJ.   +4 more
europepmc   +1 more source

Prader-Willi syndrome: Genetics, clinical symptoms, and model systems

Mayssa Saade, Wote Amelo Rike, Omveer Sharma, Ahmad Abu‐Akel, Shani Stern   +4 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Mapping the Scientific Landscape of Schizophrenia Genetics (2020-2025): A Bibliometric and Scientometric Study of Global Trends and Collaborations. [PDF]

Brain Behav
Mikaeili N, Naeim M, Narimani M.
europepmc   +1 more source

Comprehensive Clinical Genetics, Molecular and Pathological Evaluation Efficiently Assist Diagnostics and Therapy Selection in Breast Cancer Patients with Hereditary Genetic Background [PDF]

Petra Nagy, J. Papp, Vince Kornél Grolmusz, Anikó Bozsik, Tímea Pócza, Edith Oláh, Attila Patócs, Henriett Butz   +7 more
openalex   +1 more source