Results 11 to 20 of about 10,211 (221)

Revealing a New Family of D-2-Hydroxyglutarate Dehydrogenases in Escherichia coli and Pantoea ananatis Encoded by ydiJ

open access: yesMicroorganisms, 2022
In E. coli and P. ananatis, L-serine biosynthesis is initiated by the action of D-3-phosphoglycerate dehydrogenase (SerA), which converts D-3-phosphoglycerate into 3-phosphohydroxypyruvate.
Victor V. Samsonov   +5 more
doaj   +1 more source

The Escherichia coli Amino Acid Uptake Protein CycA: Regulation of Its Synthesis and Practical Application in l-Isoleucine Production

open access: yesMicroorganisms, 2022
Amino acid transport systems perform important physiological functions; their role should certainly be considered in microbial production of amino acids.
Christine Hook   +4 more
doaj   +1 more source

GENETIKA DASAR

open access: yes
Lilis Supratman, Talita Savana, Lilis Supratman, Desti Herawati, Isrotun Ngesti Utami, Ilah Nurlaelah, Bayu Widiyanto, Ibni Annas ISBN: 978-634-4-2337-2 Tebal: ix + 232 hlm., 21 x 14 cm Juli 2025 Editor: Lilis Supratman Penata Letak: Diwantika Rachman Penata Sampul: Rehan Raharjo Penerbit PT. SIGMA LITERA GLOBAL Jl. Dr. Setia Budi No. 76 Rt. 02 Rw.
Supratman, L. (Lilis)
openaire   +2 more sources

Engineering of Escherichia coli Glyceraldehyde-3-Phosphate Dehydrogenase with Dual NAD+/NADP+ Cofactor Specificity for Improving Amino Acid Production

open access: yesMicroorganisms, 2022
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme in the central metabolism of microbial cells. GAPDHs differ in cofactor specificity and use NAD+, NADP+, or both cofactors, reducing them to NADH and NADPH, respectively.
Ekaterina A. Slivinskaya   +3 more
doaj   +1 more source

H+-Translocating Membrane-Bound Pyrophosphatase from Rhodospirillum rubrum Fuels Escherichia coli Cells via an Alternative Pathway for Energy Generation

open access: yesMicroorganisms, 2023
Inorganic pyrophosphatases (PPases) catalyze an essential reaction, namely, the hydrolysis of PPi, which is formed in large quantities as a side product of numerous cellular reactions.
Evgeniya A. Malykh   +6 more
doaj   +1 more source

Comparative Analysis of Catabolic and Anabolic Dehydroshikimate Dehydratases for 3,4-DHBA Production in Escherichia coli

open access: yesMicroorganisms, 2022
The production of 3,4-dihydroxybenzoic acid (3,4-DHBA or protocatechuate) is a relevant task owing to 3,4-DHBA’s pharmaceutical properties and its use as a precursor for subsequent synthesis of high value-added chemicals.
Ekaterina A. Shmonova   +3 more
doaj   +1 more source

Depression patient-derived cortical neurons reveal potential biomarkers for antidepressant response [PDF]

open access: yesEur Psychiatry, 2021
Introduction Major depressive disorder is highly prevalent worldwide and has been affecting an increasing number of people each year. Current first line antidepressants show merely 37% remission, and physicians are forced to use a trial-and-error ...
Avior Y   +6 more
europepmc   +2 more sources

Patient iPSC-derived neurons reveal mechanisms underlying antidepressant response: a potential diagnostic tool [PDF]

open access: yesEur Psychiatry, 2023
Introduction Depression is a leading cause of disability worldwide despite dozens of approved antidepressants. There are currently no clear guidelines to assist the physician in their choice of drug, with existing tools limited to pharmacogenetics that ...
Shohat Koren S   +6 more
europepmc   +2 more sources

Optimasi Nilai Parameter pada Metode Brown’s Exponential Smoothing dengan Algoritma Multiple Genetik

open access: yesJurnal Nasional Pendidikan Teknik Informatika (JANAPATI), 2022
Untuk mendapatkan nilai alpha paling optimal untuk metode Brown's Double Exponential Smoothing (Brown's-DES) dapat menggunakan metode algoritma genetika.
Anop Sudiatmika   +2 more
doaj   +1 more source

Pure cerebellar ataxia due to bi‐allelic PRDX3 variants including recurring p.Asp202Asn

open access: yesAnnals of Clinical and Translational Neurology, Volume 10, Issue 10, Page 1910-1916, October 2023., 2023
Abstract Bi‐allelic variants in peroxiredoxin 3 (PRDX3) have only recently been associated with autosomal recessive spinocerebellar ataxia characterized by early onset slowly progressive cerebellar ataxia, variably associated with hyperkinetic and hypokinetic features, accompanied by cerebellar atrophy and occasional olivary and brainstem involvement ...
Stephanie Efthymiou   +15 more
wiley   +1 more source

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