Supraspinal gene transfer by intrathecal adeno-associated virus serotype 5
We report the pattern of transgene expression across brain regions after intrathecal delivery of adeno-associated virus serotype 5 (AAV5). Labeling in hindbrain appeared to be primarily neuronal, and was detected in sensory nuclei of medulla, pontine ...
Daniel J. Schuster+10 more
doaj +1 more source
BOLD-fMRI in the mouse auditory pathway [PDF]
The auditory pathway is widely distributed throughout the brain, and is perhaps one of the most interesting networks in the context of neuroplasticity. Accurate mapping of neural activity in the entire pathway, preferably noninvasively, and with high resolution, could be instrumental for understanding such longitudinal processes.
arxiv +1 more source
Altered white matter connectivity associated with visual hallucinations following occipital stroke [PDF]
Introduction: Visual hallucinations that arise following vision loss stem from aberrant functional activity in visual cortices and an imbalance of activity across associated cortical and subcortical networks subsequent to visual pathway damage. We sought
Rafique, Sara+2 more
core +1 more source
Fast frequency modulation is encoded according to the listener expectations in the human subcortical auditory pathway [PDF]
Expectations aid and bias our perception. In speech, expected words are easier to recognise than unexpected words, particularly in noisy environments, and incorrect expectations can make us misunderstand our conversational partner. Expectations are combined with the output from the sensory pathways to form representations of speech in the cerebral ...
arxiv
Dorsal lateral geniculate substructure in the Long-Evans rat: A cholera toxin B-subunit study [PDF]
This study describes the substructure of the dorsal lateral geniculate nucleus of the thalamus of the pigmented rat (Rattus norvegicus) based on the eye-of-origin of its retinal ganglion cell inputs. We made monocular intra-ocular injections of the B-subunit of cholera toxin (CTB), a sensitive anterograde tracer, in three adult male Long-Evans rats. In
arxiv +1 more source
Niche sharing reflects a poorly understood biodiversity phenomenon [PDF]
Eucalyptus spp. are susceptible to a large number of foliar pathogens, some of which can cause serious defoliation and die-back. In this study, a single leaf spot on a Eucalyptus leaf collected in Madagascar revealed an unusual association of microfungi ...
Crous, P.W.+2 more
core +3 more sources
A key parameter to constrain predictive, bottom-up circuit models of a given brain domain is the number and position of the neuronal populations involved.
Marian Evangelio+2 more
doaj +1 more source
Concurrent generative models inform prediction error in the human auditory pathway [PDF]
Predictive coding is the leading algorithmic framework to understand how expectations shape our experience of reality. Its main tenet is that sensory neurons encode prediction error: the residuals between a generative model of the sensory world and the actual sensory input.
arxiv
Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC+5 more
core +2 more sources
Can retinal ganglion cell dipoles seed iso-orientation domains in the visual cortex? [PDF]
It has been argued that the emergence of roughly periodic orientation preference maps (OPMs) in the primary visual cortex (V1) of carnivores and primates can be explained by a so-called statistical connectivity model.
Eglen, Stephen J.+3 more
core +8 more sources