Results 101 to 110 of about 2,072,884 (197)

Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang   +7 more
wiley   +1 more source

Prospective Evaluation of Quality‐of‐Life Improvement After Dapagliflozin Initiation in a Greek Population With HFrEF: The EVOLUTION‐HF 12‐Month Results

open access: yesClinical Cardiology, Volume 49, Issue 9, September 2026.
Among patients with HFrEF, initiation of dapagliflozin resulted in significant improvements in quality of life, as demonstrated by increased KCCQ‐23 scores during follow‐up. ABSTRACT Introduction Heart failure with reduced ejection fraction (HFrEF), defined by a left ventricular ejection fraction ≤ 40%, remains a major global health challenge ...
Victoria Potoupni   +31 more
wiley   +1 more source

Cinnamaldehyde From Cinnamon as a Food‐Derived Bioactive: Phytochemistry, Anticancer Mechanisms, Bioavailability, Nanoformulation and Safety

open access: yesFood Frontiers, Volume 7, Issue 5, September 2026.
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi   +6 more
wiley   +1 more source

Rare neoplasms

open access: yes, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
Valentina Ciaravino   +11 more
core   +1 more source

Simplified PCR for detection of Haemophilus ducreyi and diagnosis of chancroid [PDF]

open access: yes, 1995
A simplified PCR was developed for detection of Haemophilus ducreyi in samples from chancroid patients. The strategy included a straightforward chloroform extraction sample preparation method, a one-tube nested PCR to minimize contamination risks, and a ...
Wilson, S.M   +6 more
core   +2 more sources

Residence Near Agricultural Crops at Birth and Risk of Adult Testicular Germ Cell Tumors: A French Nationwide Case–Control Study Using Historical Aerial GIS Data

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1153-1166, 1 September 2026.
As the incidence of testicular germ cell tumors (TGCTs) rises, prenatal exposure to agricultural pesticides may represent an important risk factor. Here, geographic information system‐based measures of farmland proximity at birth were used as a proxy for early‐life pesticide exposure in France, a major pesticide consumer.
Aurélie M. N. Danjou   +75 more
wiley   +1 more source

Practice Patterns in Extramammary Paget's Disease

open access: yesJEADV Clinical Practice, Volume 5, Issue 3, Page 922-924, September 2026.
ABSTRACT Background In patients with Extramammary Paget's Disease (EMPD), a rare intraepithelial adenocarcinoma, wide local excision (WLE) has historically been the standard of treatment despite high rates of positive margins and recurrence. Mohs micrographic surgery (MMS) has demonstrated superior outcomes, yet practice patterns vary due to limited ...
Yasmine Mohseni   +4 more
wiley   +1 more source

Metabolic Syndrome: From Mechanisms to Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 9, September 2026.
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy   +3 more
wiley   +1 more source

Health is male's business too : NT Indigenous Male Health Conference, Tennant Creek, 29-31 August, 2000 : a report on the indigenous male health movement in the Northern Territory.

open access: yes, 2000
This conference report has been prepared by the Male Health Policy Unit, within Territory Health Services, on behalf of the NT Indigenous Male Health Committee. It is essentially a descriptive recording of the information exchanged, the issues raised and

core  

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