CAR-T Cells in the Treatment of Urologic Neoplasms: Present and Future [PDF]
Frontiers in Oncology, 2022 In recent years, with the breakthrough of CAR-T cells in the treatment of hematological tumors, they are increasingly being used to treat solid tumors, including urologic neoplasms.
Zhengchao Zhang
exaly +6 more sources
Targeting c-Met in the treatment of urologic neoplasms: Current status and challenges [PDF]
Frontiers in Oncology, 2023 At present, studies have found that c-Met is mainly involved in epithelial-mesenchymal transition (EMT) of tumor tissues in urologic neoplasms. Hepatocyte growth factor (HGF) combined with c-Met promotes the mitosis of tumor cells, and then induces ...
Pengxiao Su, Ming Zhang, Xin Kang
exaly +6 more sources
Microbiome in urologic neoplasms: focusing on tumor immunity [PDF]
Frontiers in ImmunologyUrological tumors are an important disease affecting global human health, and their pathogenesis and treatment have been the focus of medical research.
Jun Zou +5 more
doaj +4 more sources
Global, regional, and National burden of urologic neoplasms from 1990 to 2021 and future projections to 2050, a comprehensive analysis for global burden of disease [PDF]
Discover OncologyBackground Urologic neoplasms are considered to pose a serious threat to patients’ lives and quality of life. Analyzing and describing the global disease burden of urologic neoplasms is necessary.
Zhao Yang +4 more
exaly +3 more sources
Updates in Histologic Grading of Urologic Neoplasms [PDF]
Archives of Pathology and Laboratory Medicine, 2020 Context.— Tumor histology offers a composite view of the genetic, epigenetic, proteomic, and microenvironmental determinants of tumor biology. As a marker of tumor histology, histologic grading has persisted as a highly relevant factor in risk stratification and management of urologic neoplasms (ie, renal cell ...
Chin-Lee Wu, Kristine Cornejo
exaly +3 more sources
Urinary microbiome profile in men with genitourinary malignancies [PDF]
Investigative and Clinical Urology, 2022 Purpose: Recent advances in molecular biology technology have allowed identification of microbial communities in the urinary tract, and urinary microbiome is associated with various urological diseases. In this study, we aimed to characterize the urinary
Hyun Kyu Ahn +3 more
doaj +1 more source
Management of bladder tumors in pregnancy: A case of tumor prolapse and avulsion during labor
Urology Case Reports, 2021 Pregnancy presents unique obstacles to diagnosis and management of urologic disease. We present a case of a primigravid female with clot retention requiring evacuation in the operating room due to the avulsion of a bladder mass which prolapsed during ...
Kate A. Hanson +5 more
doaj +1 more source
Epidemiology of Urologic Cancer in Korea: Nationwide Trends in the Last 2 Decades [PDF]
Journal of Urologic Oncology, 2023 Purpose This study assessed recent trends in the incidence of urologic cancer and patient survival in Korea. Materials and Methods The incidence of urologic cancer in Korea was calculated based on the Korea National Cancer Incidence Database and the ...
Sang Heon Han, Hyeong Dong Yuk
doaj +1 more source
Biomolecules, 2021 Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation reaction of nicotinamide, using S-adenosyl-L-methionine as the methyl donor. Enzyme overexpression has been described in many non-neoplastic diseases, as well as in a wide range of solid
Roberto Campagna +6 more
doaj +1 more source
Geographical disparities in survival rates for urological cancers in Poland from 2000 to 2015
Nowotwory, 2023 INTRODUCTION: In 2020 in Poland, urological cancers (testis, prostate, kidney, urinary bladder) accounted for 32% of cancer incidence among men and 5% among women. There has been an improvement in the survival rate for urological cancers in recent years.
Klaudia Barańska +4 more
doaj +1 more source