Results 141 to 150 of about 74,484 (232)

Single‐center experience with bimekizumab in psoriasis patients with previous exposure to interleukin‐17 inhibitors

open access: yes
International Journal of Dermatology, EarlyView.
Ioannis‐Alexios Koumprentziotis   +7 more
wiley   +1 more source

Efficacy of human papillomavirus vaccines in the prevention of male genital diseases: a systematic review

open access: yesBJU International, Volume 135, Issue 6, Page 902-907, June 2025.
Objectives To evaluate the results of randomised controlled trials (RCTs) regarding the efficacy of human papillomavirus (HPV) vaccination in preventing male genital‐related diseases. Methods A systematic search of English language literature using PubMed, Scopus, and Cochrane Library was performed in April 2024 according to the Preferred Reporting ...
Mehdi Kardoust Parizi   +7 more
wiley   +1 more source

DNA methylation and copy number alterations in the progression of HPV‐associated high‐grade vulvar intraepithelial lesion

open access: yesInternational Journal of Cancer, Volume 156, Issue 10, Page 1926-1935, 15 May 2025.
What's new? Patients with human papillomavirus (HPV)‐associated high‐grade vulvar intraepithelial lesion (HSIL) often undergo damaging treatments to prevent progression to cancer. Molecular characterization of HSIL to assess progression risk could reduce the need for aggressive interventions. Here, cancer risk stratification of HSIL was investigated by
Flavia Runello   +8 more
wiley   +1 more source

DAPK3 is Essential for DBP‐Induced Autophagy of Mouse Leydig Cells

open access: yesAdvanced Science, Volume 12, Issue 17, May 8, 2025.
This study has confirmed that death‐associated protein kinase 3 (DAPK3) is essential for dibutyl phthalate (DBP)‐induced autophagy of mouse Leydig cells, and is regulated by both transcription factor specific protein 2 (Sp2) and parkin RBR E3 ubiquitin‐protein ligase (PRKN), and melatonin can alleviate DBP‐induced autophagy of the cells.
Si Yang   +4 more
wiley   +1 more source

An Update on the Nutritional and Therapeutic Potential of Dioscorea oppositifolia

open access: yesFood Science &Nutrition, Volume 13, Issue 5, May 2025.
Dioscorea oppositifolia L. (Cinnamon vine) contains bioactive compounds, such as diosgenin, demonstrating anticancer properties. Diosgenin inhibits JAK/STAT3 signaling, suppressing cell proliferation, invasion and metastasis. Additionally, it triggers mitochondrial apoptosis by activating Bax, promoting cytochrome C release and stimulating caspase‐9 ...
Ruchika Kumari   +10 more
wiley   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

open access: yesGlobal Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze   +8 more
wiley   +1 more source

Marburg Virus Disease: A Narrative Review

open access: yesHealth Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati   +4 more
wiley   +1 more source

Transgenerational Reproductive and Developmental Toxicity Induced by N‐Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster

open access: yesJournal of Applied Toxicology, Volume 45, Issue 5, Page 841-857, May 2025.
ABSTRACT N‐Nitrosodimethylamine (NDMA) is a known water disinfection byproduct (DBP) characterized as a potent hepatotoxin, promutagen, and probable human carcinogen; this is because of the metabolites associated with its biotransformation. The metabolism of NDMA produces formaldehyde, another alkylating agent and DBP. Both compounds are generated from
Oscar Eduardo Tabares‐Mosquera   +3 more
wiley   +1 more source

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