Results 151 to 160 of about 74,484 (232)

β3‐Adrenoceptor Agonism to Mimic the Biological Effects of Intrauterine Hypoxia: Taking Great Strides Toward a Pharmacological Artificial Placenta

Medicinal Research Reviews, Volume 45, Issue 3, Page 842-866, May 2025.
ABSTRACT At different stages of life, from embryonic to postnatal, varying oxygen concentrations modulate cellular gene expression by enhancing or repressing hypoxia‐inducible transcription factors. During embryonic/fetal life, these genes encode proteins involved in adapting to a low‐oxygen environment, including the induction of specific enzymes ...
Luca Filippi, Francesca Innocenti, Francesca Pascarella, Rosa Teresa Scaramuzzo, Riccardo Morganti, Paola Bagnoli, Maurizio Cammalleri, Massimo Dal Monte, Maura Calvani, Alessandro Pini   +9 more
wiley   +1 more source

Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development

Molecular Reproduction and Development, Volume 92, Issue 5, May 2025.
ABSTRACT Germ cells are pivotal for the continuation of biological species. The metazoan germline develops from primordial germ cells (PGCs) that undergo multiple rounds of mitotic divisions. The PGCs are specified by either maternal inheritance of asymmetrically polarized cytoplasmic mRNAs/proteins (found in roundworms, flies, fishes, frogs, and fowl)
Indrashis Bhattacharya, Lakshmi K. Nalinan, K. V. Anusree, Ahmed Saleel, Aditi Khamamkar, Souvik Dey   +5 more
wiley   +1 more source

The Prognostic Value of the Prostate Adenocarcinoma With Ductal Feature in Patients With Advanced Prostate Cancer Treated With Abiraterone Acetate

The Prostate, Volume 85, Issue 7, Page 659-669, May 15, 2025.
ABSTRACT Background The prognostic value of the prostate adenocarcinoma (PAC) with ductal feature in patients with advanced prostate cancer treated with abiraterone acetate has not been scrutinized. This study aims to explore the predictive value of PAC with ductal feature on the therapeutic efficacy of abiraterone therapy in metastatic prostate cancer
Yifu Shi, Xinyuan Wei, Fengnian Zhao, Junru Chen, Guangxi Sun, Xingming Zhang, Jiayu Liang, Xu Hu, Pengfei Shen, Zhenhua Liu, Ling Nie, Ni Chen, Jinge Zhao, Hao Zeng   +13 more
wiley   +1 more source

Loop‐Mediated Isothermal Amplification (LAMP) for the Diagnosis of Sexually Transmitted Infections: A Review

Microbial Biotechnology, Volume 18, Issue 5, May 2025.
LAMP assay for point‐of‐care tests. ABSTRACT Sexually transmitted infections (STIs) remain a significant public health concern. Given the asymptomatic nature of many STIs, diagnostic testing is critical for determining the appropriate treatment, enabling effective tracing and reducing the risk of further transmission.
Yasaman Ahmadi, Yejiong Yu, Zhanfeng Cui, Wei E. Huang, Monique I. Andersson   +4 more
wiley   +1 more source

Epidemiology and treatment of Adamantiades–Behçet's disease in Germany: A healthcare claims database study

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 1017-1027, May 2025.
Epidemiology, associated comorbidities and current treatment patterns of Adamantiades–Behçet's disease in Germany. Abstract Background Adamantiades–Behçet's disease (ABD) is a rare, chronic, relapsing, multisystem vasculitis, with a reported prevalence of 0.9 out of 100,000 population in Germany in 2012.
C. C. Zouboulis, J. Borchert, J. Diesing, R. Heinrich, W. Galetzka, J.‐P. Medelnik, A. Altenburg, A. Feldhus, T. Schönfelder   +8 more
wiley   +1 more source

Primary Extramammary Paget's Disease in a Male Patient Exhibiting Genital Involvement Mimicking Clinical and Histopathological Features of Bowen's Disease: A Case Report. [PDF]

Cureus
Gómez López DE, Chávez-Rojas AJ, Gómez Flores EJ, Miranda I, Ancona Castro C, Suro Santos Y.   +5 more
europepmc   +1 more source

Birth defects and cancer risk : Nordic population-based studies of cancer risk in children, adolescents, and adults with major birth defects and their siblings [PDF]

Bakgrunn: Medfødte misdannelser og kreft er begge blant de ti vanligste årsakene til tapte leveår grunnet død eller helsetap for barn mellom 0 og 19 år (ulykker og perinatale sykdommer ekskludert).
Daltveit, Dagrun Slettebø
core  

Different Intensities of Physical Activity and Risk of Male Genital Cancers: Exploring Potential Causal Relationships. [PDF]

Am J Mens Health
Zhen K, Huo L, Zhu T, Li Y.
europepmc   +1 more source

Immunochemical and molecular assessment of urothelial neoplasms and aspects of the 2016 World Health Organization classification

Histopathology, 2016
E. Compérat, J. Varinot
semanticscholar   +1 more source

Clinical presentations and complications of lichen sclerosus: A systematic review. [PDF]

J Dtsch Dermatol Ges
Conte S, Mohamed SD, Cohen Y, Yacovelli A, Starkey S, Johnston L, Shergill M, Law A, Litvinov IV, Mukovozov I.   +9 more
europepmc   +1 more source