Results 51 to 60 of about 25,291 (189)

Prognosis and Toxicity Stratified by Best Tumor Burden Change in Japanese Patients With Advanced Melanoma Treated With First‐Line Programmed Cell Death Protein 1 Monotherapy

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have significantly improved outcomes in patients with advanced malignant melanoma (MM). However, more than half of patients receiving anti‐programmed cell death protein‐1 (PD‐1) antibody monotherapy still fail to respond, with response rates varying by race and melanoma subtype.
Ken Horisaki, Shusuke Yoshikawa, Wataru Omata, Arata Tsutsumida, Yoshio Kiyohara   +4 more
wiley   +1 more source

Postoperative Complications and Risk Factors in Skin Tumor Excision With Simple Suturing Under Local Anesthesia: A Multicenter Retrospective Study in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Skin tumor excision under local anesthesia with simple suturing is widely performed in outpatient dermatological practice. Although generally considered safe, postoperative complications such as wound dehiscence, infection, and contact dermatitis can negatively impact patients' quality of life and healthcare resources.
Kasumi Kato, Hiroshi Kato, Tetsuya Magara, Akimichi Morita   +3 more
wiley   +1 more source

C‐Reactive Protein Kinetics as Prognostic Biomarkers in Stage IV‐Melanoma Treated With Immune Checkpoint Inhibitors in the Japanese Population: A Single‐Center, Retrospective Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Malignant melanoma is an aggressive form of skin cancer with variable outcomes in response to immunotherapy. Although immune checkpoint inhibitors have improved survival in patients with advanced melanoma, predicting which patients will benefit from treatment remains a major clinical challenge. This study aimed to evaluate the prognostic value
Ken Horisaki, Shusuke Yoshikawa, Wataru Omata, Arata Tsutsumida, Yoshio Kiyohara   +4 more
wiley   +1 more source

Individualized T3‐4N+ Rectal Cancer Treatment Strategies: Exploring the Efficacy of Preoperative Synchronized Lateral Lymph Node Simultaneous Integrated Boost Radiation Therapy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Anatomical Diagram: It shows a cross‐section of the pelvic area highlighting the rectum and lateral lymph nodes, which are the focal points of the treatment strategy discussed in the paper. Flowchart: It outlines the treatment process from preoperative synchronized radiation therapy to the subsequent surgical procedures, illustrating the sequence of ...
Xinjue Shi, Siyao Zhong, Xianbin Zheng, Xianxiu Nan, Xuan Liu, Qiteng Liu, Jing Yuan, Yuyan Gao   +7 more
wiley   +1 more source

Is there a causal association between genotoxicity and the imposex effect? [PDF]

, 2007
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Depledge, Michael H., Galloway, Tamara S., Hagger, Josephine A., Jobling, Susan, Oehlmann, Jörg   +4 more
core  

Immunophenotypic Comparison of Testicular Sclerosing Sertoli Cell Tumors and Sertoli Cell Tumors Not Otherwise Specified [PDF]

, 2017
Testicular Sertoli cell tumors (SCTs) are rare, and most fall into the category of SCT–not otherwise specified (SCT-NOS). Only a few additional types of SCT are recognized.
Manivel, Juan C., Mesa, Hector, Ulbright, Thomas M., Zhang, Chen   +3 more
core   +1 more source

Normozoospermic men in infertile couples: Potential benefit of early medical diagnostic procedures

Andrology, EarlyView.
Abstract Introduction Infertility, defined as the inability to achieve pregnancy despite regular, unprotected sexual intercourse for 1 year, affects approximately 15% of couples. Male factors contribute to 50% of these cases. The necessity of andrological evaluations for male partners of infertile couples with normozoospermia is currently under ...
Simone Bier, Anton Wolff, Michael Zitzmann, Sabine Kliesch   +3 more
wiley   +1 more source

Malignant neoplasms of male genital organs (C60-C63) in the Osijek-Baranja County, Croatia.

Collegium antropologicum, 2015
Cancers of male genital organs (C60-C63) and in particular, prostate cancer, represent one of the most frequent cancer groups among males in economically developed countries and growing cancer group in developing countries. The Institute of Public Health of the Osijek-Baranja County in collaborate with different county institutes provide updated ...
Josip, Milas, Senka, Samaržić, Kreŝimir, Milas   +2 more
openaire   +1 more source

Multilocular Cystic Renal Cell Carcinoma: An Unusual Gross Appearance [PDF]

, 2011
Multilocular Cystic Renal Cell Carcinoma (MCRCC) represents a rare variant of clear cell (conventional) renal cell carcinomas. Attributable to its distinct characteristics in prognosis and its natural history, MCRCC was recognised as a separate subtype ...
Jagtap, SV, Jain, G, Mali, RK, Nikumbh, DB   +3 more
core   +1 more source

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

Andrology, EarlyView.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody, Daniela Fietz, Benedict Nathaniel, Mark Frydenberg, Ben Tran, Hans‐Christian Schuppe, Kate L. Loveland   +6 more
wiley   +1 more source