Results 71 to 80 of about 66,106 (160)

Sexual Selection on Non‐Ornamental Traits Is Underpinned by Evidence of Genetic Constraints on Sex‐Biased Expression in Dusky Pipefish

Molecular Ecology, EarlyView.
ABSTRACT Species lacking distinct secondary sex characteristics, such as differences in size or morphology, are often thought to experience lower levels of sex‐specific selection in comparison to highly sexually dimorphic organisms. However, monomorphism in classic visible traits could be a result of genetic or physiological constraints that prevent ...
Nicole M. Tosto, Emily Rose, Heather D. Mason, Judith E. Mank, Sarah P. Flanagan   +4 more
wiley   +1 more source

Demystifying “Hyaline Angiopathy” of Pulse Granuloma in Oral and Extraoral Surgical Pathology

Oral Diseases, EarlyView.
ABSTRACT Background and Objectives Pulse granuloma (PG), or giant cell hyaline angiopathy, is an immune‐mediated reaction often following the implantation of plant‐derived food particles. PGs are primarily found in the oral cavity and gastrointestinal tract and may represent a histopathological pitfall, being mistaken for other granulomatous conditions
Felipe Fornias Sperandio, Matheus de Castro Costa, Marina Lara de Carli, Rani Kanthan   +3 more
wiley   +1 more source

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Germ cell and other tumors in individuals with differences in sex development

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel, Miguel Reyes‐Múgica   +1 more
wiley   +1 more source

Hyaluronan accumulation is associated with reduced hyaluronidase expression in renal cell carcinoma, with CD44, HAS1, and HYAL2 emerging as prognostic markers

The Journal of Pathology: Clinical Research, Volume 11, Issue 4, July 2025.
Abstract Hyaluronan (HA), a large extracellular matrix glycosaminoglycan, is associated with malignant features in several human cancers. The accumulation of HA in renal cell carcinomas (RCC) correlates with unfavorable outcomes, higher tumor grade, and more advanced disease stages.
Otto Jokelainen, Teemu Rintala, Satu Remes, Sanna Pasonen‐Seppänen, Timo K Nykopp, Reijo Sironen   +5 more
wiley   +1 more source

Developmental Disturbances in Animal Models of Autism Spectrum Disorder

Developmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Although the early signs of autism spectrum disorder (ASD) are widely studied, the significant ambiguity and heterogeneity in symptoms require the comparison of available models, approaches, and the search for common denominators and key indicators.
Kristof Laszlo, Zuzana Bacova, Dora Zelena, Jan Bakos   +3 more
wiley   +1 more source

Alternative MYB Promoter Activity Is a Potential Prognostic Biomarker in Head and Neck Adenoid Cystic Carcinoma

Head &Neck, Volume 47, Issue 7, Page 1996-2002, July 2025.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is an aggressive therapy‐resistant head and neck cancer with a high frequency of local recurrences and distant metastases. Activation of the MYB gene, encoding an oncogenic master transcription factor, is the key genomic hallmark of ACC and a potential therapeutic target. Here, we have investigated the
Fredrik Jäwert, André Fehr, Marta Persson, Adel K. El‐Naggar, Göran Stenman, Mattias K. Andersson   +5 more
wiley   +1 more source

The Interplay of Cross‐Organ Immune Regulation in Inflammation and Cancer

MedComm, Volume 6, Issue 7, July 2025.
Organs interact dynamically through immune regulation, influencing systemic immune responses and disease progression. We review molecular and cellular mechanisms of cross‐organ immune regulation in inflammation and cancer, focusing on gut, liver, and brain interactions with other organs.
Jie Dou, Jinzuo Jiang, Yangtao Xue, Xiaoqi Jiang, Yongzhuo Jiang, Peng Xiao, Junjie Xu   +6 more
wiley   +1 more source

Co‐Occurrence of Ovarian Dysgerminoma‐Inducing Gonadoblastoma and Two Distinct Mammary Carcinomas in a Dog: A Case Report and Review of the Literature

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
Canine ovarian gonadoblastoma (GB) (with SALL4, OCT‐4, E‐cadherin, α‐inhibin, AE1/AE3, and WT‐1 immunoreactivity) and two mammary carcinomas have been described in a genetically normal female Spitz. The scarcity of GB in dogs, aberrant WT‐1 expression in the germ cell component, and lack of the AMELY gene are the most remarkable features of the present
Diba Golchin, Farhang Sasani, Saeed Farzad‐Mohajeri, Mohsen Tovhidifar, Iradj Ashrafi Tamai   +4 more
wiley   +1 more source

Phenotype and gene signature of testicular tumors in 129.MOLF‐Chr19 mice resemble human teratomas

Andrology, Volume 13, Issue 5, Page 1213-1222, July 2025.
Abstract Background Testicular germ cell tumor (TGCT) is the most common type of tumor in young men. Type II germ cell tumors including postpubertal‐type teratomas are derived from the germ cell neoplasia in situ (GCNIS), whereas prepubertal‐type teratomas arise independently of the GCNIS.
Fabian A. Gayer, Lucas Klaus, Sybille D. Reichardt, Alexander Fichtner, Holger M. Reichardt   +4 more
wiley   +1 more source