Results 41 to 50 of about 1,979 (262)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Der Müller Peter and (s) Fischers Emma

open access: yesNordisk Tidskrift för Socioonomastik
In German dialects and in rural communities, special personal names are used, in which the surname precedes the given name: der Müller Peter, Fischers Emma.
Theresa Schweden
doaj   +1 more source

Collapse of genitive and benefactive case in Ecuadorian Quechua?

open access: yesStellenbosch Papers in Linguistics, 2017
In Ecuadorian Quechua the markers for genitive and benefactive case have become indistinguishable in form: both are basically -pak. This squib discusses the issue whether there has also been a merger in the underlying representation, or whether they ...
Muysken, Pieter
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Zu den Schwierigkeiten beim Genitivseinsatz Dativ gegen Genitiv

open access: yesTraduction et Langues, 2013
On the difficulties in using the genitive dative as opposed to the genitive For some people, grammar is an obstacle that interferes with their language acquisition and facilitating certain grammatical rules can be an important means of optimally ...
Amina Fehama Benabdelkader
doaj  

Instrumental prepositions and case: Contexts of occurrence and alternations with datives

open access: yesGlossa, 2017
We will argue that instrumentals are the mirror image of dative/genitive obliques. We propose that both sets of adpositions/cases are elementary predicates, expressing a zonal inclusion (part-whole/possession relation); instrumentals reverse the ...
Ludovico Franco, Maria Rita Manzini
doaj   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Determination and modification: Topology of prenominal attributes in Lithuanian

open access: yesKalbotyra, 2018
[full article and abstract in English] This paper offers a description of the linear structure of the definite Lithuanian noun phrase (NP) with an emphasis on prenominal attributes.
Ringailė Trakymaitė
doaj   +1 more source

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