Results 41 to 50 of about 442,357 (177)

Transcriptome sequencing revealed differences in the response of renal cancer cells to hypoxia and CoCl2 treatment [version 1; referees: 2 approved]

open access: yesF1000Research, 2015
Human cancer cells are subjected to hypoxic conditions in many tumours. Hypoxia causes alterations in the glycolytic pathway activation through stabilization of hypoxia-inducible factor 1.
Nadezhda Zhigalova   +3 more
doaj   +1 more source

An Integrated Systematic Analysis and the Clinical Significance of Hepcidin in Common Malignancies of the Male Genitourinary System

open access: yesFrontiers in Genetics, 2022
Tumors of the male genitourinary system are of great concern to the health of men worldwide. Although emerging experiment-based evidence indicates an association between hepcidin and such cancers, an integrated analysis is still lacking. For this reason,
Xiaogang Wang   +4 more
doaj   +1 more source

A predictive model of overall survival in patients with metastatic castration-resistant prostate cancer [version 2; peer review: 2 approved]

open access: yesF1000Research, 2019
Metastatic castration resistant prostate cancer (mCRPC) is one of the most common cancers with a poor prognosis. To improve prognostic models of mCRPC, the Dialogue for Reverse Engineering Assessments and Methods (DREAM) Consortium organized a ...
Mehrad Mahmoudian   +5 more
doaj   +1 more source

Two-step feature selection for predicting survival time of patients with metastatic castrate resistant prostate cancer [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Metastatic castrate resistant prostate cancer (mCRPC) is the major cause of death in prostate cancer patients. Even though some options for treatment of mCRPC have been developed, the most effective therapies remain unclear.
Motoki Shiga
doaj   +1 more source

DWCox: A density-weighted Cox model for outlier-robust prediction of prostate cancer survival [version 1; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2016
Reliable predictions on the risk and survival time of prostate cancer patients based on their clinical records can help guide their treatment and provide hints about the disease mechanism.
Jinfeng Xiao   +7 more
doaj   +1 more source

Using complex networks for refining survival prognosis in prostate cancer patient [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Complex network theory has been used, during the last decade, to understand the structures behind complex biological problems, yielding new knowledge in a large number of situations. Nevertheless, such knowledge has remained mostly qualitative.
Massimiliano Zanin
doaj   +1 more source

Selected news from the 2014 Genitourinary Cancers Symposium: Translating novel strategies into clinical practice

open access: yes, 2014
2014 Genitourinary Cancers Symposium San Francisco, CA, USA, 30 January-1 February 2014 The American Society of Clinical Oncology symposium dedicated to genitourinary tumors represents an unmissable opportunity for the whole oncology community with a ...
Santoni M.   +10 more
core   +2 more sources

Additional file 5 of Regional gain and global loss of 5-hydroxymethylcytosine coexist in genitourinary cancers and regulate different oncogenic pathways

open access: yes, 2022
Additional file5: Fig. S5. Genes associated with hypo-5hmC alterations in genitourinary cancers clinical outcome (related to Fig. 3)
Jilu Wang (13835339)   +7 more
core   +1 more source

The germline mutational landscape of genitourinary cancers and its indication for prognosis and risk

open access: yesBMC Urology, 2022
Background Germline mutations represent a high risk of hereditary cancers in population. The landscape and characteristics of germline mutations in genitourinary cancer are largely unknown, and their correlation with patient prognosis has not been ...
Yong Yang   +6 more
doaj   +1 more source

The Role of C-Reactive Protein in Kidney, Bladder, and Prostate Cancers

open access: yesFrontiers in Immunology, 2021
C-Reactive Protein (CRP) is associated with diverse outcomes in patients with, or suspected to have, genitourinary malignancies. CRP levels have been shown to be associated with the probability of a prostate cancer diagnosis in patients with elevated PSA,
Daniel O’Brian   +5 more
doaj   +1 more source

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