Results 1 to 10 of about 86 (60)

Accuracy benchmark of the GeneMind GenoLab M sequencing platform for WGS and WES analysis [PDF]

BMC Genomics, 2022
Background GenoLab M is a recently developed next-generation sequencing (NGS) platform from GeneMind Biosciences. To establish the performance of GenoLab M, we present the first report to benchmark and compare the WGS and WES sequencing data of the ...
Chaoyang Li, Xue Fan, Xin Guo, Yongfeng Liu, Miao Wang, Xiao Chao Zhao, Ping Wu, Qin Yan, Lei Sun   +8 more
doaj   +5 more sources

Comparative performance of the GenoLab M and NovaSeq 6000 sequencing platforms for transcriptome and LncRNA analysis [PDF]

BMC Genomics, 2021
Background GenoLab M is a recently established next-generation sequencing platform from GeneMind Biosciences. Presently, Illumina sequencers are the globally leading sequencing platform in the next-generation sequencing market. Here, we present the first
Yongfeng Liu, Ran Han, Letian Zhou, Mingjie Luo, Lidong Zeng, Xiaochao Zhao, Yukun Ma, Zhiliang Zhou, Lei Sun   +8 more
doaj   +6 more sources

Comparison of the Illumina NextSeq 2000 and GeneMind Genolab M sequencing platforms for spatial transcriptomics [PDF]

BMC Genomics, 2023
Background The Illumina sequencing systems demonstrate high efficiency and power and remain the most popular platforms. Platforms with similar throughput and quality profiles but lower costs are under intensive development. In this study, we compared two
Iamshchikov Pavel, Larionova Irina, Gerashchenko Tatiana, Piankov Denis, Koshkin Philipp, Korostelev Sergei, Denisov Evgeny   +6 more
doaj   +5 more sources

Correction to: Comparative performance of the GenoLab M and NovaSeq 6000 sequencing platforms for transcriptome and LncRNA analysis [PDF]

BMC Genomics, 2022
Yongfeng Liu, Ran Han, Letian Zhou, Mingjie Luo, Lidong Zeng, Xiaochao Zhao, Yukun Ma, Zhiliang Zhou, Lei Sun   +8 more
doaj   +4 more sources

Genetic characterization of human adenoviruses in patients using metagenomic next-generation sequencing in Hubei, China, from 2018 to 2019 [PDF]

Frontiers in Microbiology, 2023
ObjectivesThis study aimed to characterize the genomic epidemiology of human adenoviruses (HAdVs) in Hubei, China, using metagenomic next-generation sequencing (mNGS).MethodsIn total, 25 HAdV-positive samples collected from 21 pediatric patients were ...
Bin Fang, Juan Lai, Yongfeng Liu, Tian-tian Yu, Xiao Yu, Xiang Li, Lijun Dong, Xin Zhang, Wei Yang, Qin Yan, Lei Sun, Lin-lin Liu   +11 more
doaj   +2 more sources

Systematic and benchmarking studies of pipelines for mammal WGBS data in the novel NGS platform [PDF]

BMC Bioinformatics, 2023
Background Whole genome bisulfite sequencing (WGBS), possesses the aptitude to dissect methylation status at the nucleotide-level resolution of 5-methylcytosine (5-mC) on a genome-wide scale. It is a powerful technique for epigenome in various cell types,
Qun-ting Lin, Wei Yang, Xin Zhang, Qi-gang Li, Yong-feng Liu, Qin Yan, Lei Sun   +6 more
doaj   +2 more sources

Comparative analysis of four sequencing platforms for methylation sequencing [PDF]

BMC Research Notes
This study conducts a comprehensive assessment of four sequencing platforms: GenoLab M (Genemind), NovaSeq X (Illumina), T7 (MGI) and Salus Pro (Salus), focusing on different performance metrics related to methylation data.
Jinxia Guan, Chuanchun Yang, Hongjun Gao, Shuanping Liu, Min Zheng, Yongjun Li, Baochen Du, Changling Zhang, Yuanyuan Guo, Qi Wang, Luyang Zhao, XiaoLiang Han   +11 more
doaj   +2 more sources

Single-Cell Analysis of Preeclamptic Cord Blood Mononuclear Cells Revealed Activation of Heme-Associated Signalling Pathways. [PDF]

J Cell Mol Med
ABSTRACT Preeclampsia is a severe gestational complication whose molecular pathogenesis remains poorly understood despite extensive research. It is now recognized that both maternal and fetal cells contribute to disease progression. Notably, single‐cell RNA sequencing of cord blood cells from preeclamptic pregnancies has not been previously ...
Vishnyakova P, Karpulevich E, Karyagina V, Gantsova E, Trofimovich Y, Kiseleva V, Chirkova M, Gerashchenko T, Lokhonina A, Muminova K, Khodzhaeva Z, Denisov E, Elchaninov A, Fatkhudinov T, Sukhikh G.   +14 more
europepmc   +2 more sources

Analytical and Clinical Validation of Solo-Test Driver: A Targeted Amplicon-Based NGS Test-System for FFPE and cfDNA Analysis in Clinical Oncology Setting. [PDF]

J Clin Lab Anal
With the growing demand for compact next‐generation sequencing (NGS) test systems tailored to meet key needs in oncology, the Solo‐test Driver panel serves as a valuable tool for companion diagnostics of solid tumors, demonstrating high reliability, sensitivity, and specificity in line with established guidelines. In this work, we outline the framework
Ivanov M, Lebedeva A, Belova E, Grigoreva T, Veselovsky E, Kavun A, Taraskina A, Kuznetsova O, Nikulin V, Belyaeva L, Kravchuk D, Lisitsa T, Barinov A, Pospekhova N, Aliyarova S, Khomenko E, Tryakin A, Demidova I, Stroganova A, Fedyanin M, Mileyko V.   +20 more
europepmc   +2 more sources

Assessing the impact of sequencing platforms and analytical pipelines on whole-exome sequencing [PDF]

Frontiers in Genetics
Yanping Sun, Xiaochao Zhao, Xue Fan, Miao Wang, Chaoyang Li, Yongfeng Liu, Ping Wu, Qin Yan, Lei Sun   +8 more
doaj   +2 more sources