Results 211 to 220 of about 353,350 (233)
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Bacterial Genome Reengineering
2011The web application PrimerPair at ecogene.org generates large sets of paired DNA sequences surrounding- all protein and RNA genes of Escherichia coli K-12. Many DNA fragments, which these primers amplify, can be used to implement a genome reengineering strategy using complementary in vitro cloning and in vivo recombineering. The integration of a primer
Jindan, Zhou, Kenneth E, Rudd
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2012
Annotation of prokaryotic sequences can be separated into structural and functional annotation. Structural annotation is dependent on algorithmic interrogation of experimental evidence to discover the physical characteristics of a gene. This is done in an effort to construct accurate gene models, so understanding function or evolution of genes among ...
Nicholas, Beckloff +3 more
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Annotation of prokaryotic sequences can be separated into structural and functional annotation. Structural annotation is dependent on algorithmic interrogation of experimental evidence to discover the physical characteristics of a gene. This is done in an effort to construct accurate gene models, so understanding function or evolution of genes among ...
Nicholas, Beckloff +3 more
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BioDrugs, 2002
The sequencing of entire bacterial genomes is becoming increasingly routine, promising to revolutionise approaches to identifying putative antimicrobial drug targets. In silico methods can be used to identify putative gene products by comparing sequences of biochemically characterised enzymes and proteins with data produced by sequencing projects ...
Brian, Fritz, Gregory A, Raczniak
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The sequencing of entire bacterial genomes is becoming increasingly routine, promising to revolutionise approaches to identifying putative antimicrobial drug targets. In silico methods can be used to identify putative gene products by comparing sequences of biochemically characterised enzymes and proteins with data produced by sequencing projects ...
Brian, Fritz, Gregory A, Raczniak
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Evolution of bacterial genomes
Antonie van Leeuwenhoek, 1997This review examines evolution of bacterial genomes with an emphasis on RNA based life, the transition to functional DNA and small evolving genomes (possible plasmids) that led to larger, functional bacterial genomes.
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Proceedings of the International Conference on Bioinformatics, Computational Biology and Biomedical Informatics, 2013
Bacterial genomes at NCBI represent a large collection of strains with different levels of sequence and assembly quality as well as sampling density. Among these, there are densely-sampled sets of related genomes, usually human pathogens, whose organization and protein content could be directly analyzed within the concept of pan-genome.
Leonid Zaslavsky +2 more
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Bacterial genomes at NCBI represent a large collection of strains with different levels of sequence and assembly quality as well as sampling density. Among these, there are densely-sampled sets of related genomes, usually human pathogens, whose organization and protein content could be directly analyzed within the concept of pan-genome.
Leonid Zaslavsky +2 more
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The Ingenuity of Bacterial Genomes
Annual Review of Microbiology, 2020The genomes of bacteria contain fewer genes and substantially less noncoding DNA than those of eukaryotes, and as a result, they have much less raw material to invent new traits. Yet, bacteria are vastly more taxonomically diverse, numerically abundant, and globally successful in colonizing new habitats compared to eukaryotes.
Paul C, Kirchberger +2 more
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2015
The study of bacterial genetics has revolutionised with the development of genome sequencing, which let us catalogue the gene content of various clinically and industrially important bacteria and opened up the field of comparative genomics. The research findings on bacterial genetics were further enhanced by the development of allied techniques that ...
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The study of bacterial genetics has revolutionised with the development of genome sequencing, which let us catalogue the gene content of various clinically and industrially important bacteria and opened up the field of comparative genomics. The research findings on bacterial genetics were further enhanced by the development of allied techniques that ...
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Bacterial phytopathogens and genome science
Current Opinion in Microbiology, 2005There are now fourteen completed genomes of bacterial phytopathogens, all of which have been generated in the past six years. These genomes come from a phylogenetically diverse set of organisms, and range in size from 870 kb to more than 6Mb. The publication of these annotated genomes has significantly helped our understanding of bacterial plant ...
João C, Setubal +2 more
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Microbe Magazine, 2008
One central microbiological question is what factors change the size and content of bacterial genomes. What causes such genomes to become smaller for microbes that live as intracellular parasites or as symbionts, and what novel functions do they incorporate and stably maintain? From comparative sequence analyses during the past decade, we know that the
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One central microbiological question is what factors change the size and content of bacterial genomes. What causes such genomes to become smaller for microbes that live as intracellular parasites or as symbionts, and what novel functions do they incorporate and stably maintain? From comparative sequence analyses during the past decade, we know that the
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Evolution of the Bacterial Genome
Annual Review of Microbiology, 1978Until recently relatively few studies have been aimed directly at the subject of evolution of the bacterial genome, no doubt for the very good reason that the means to address relevant questions have not been at hand. We hope to show that this situation is beginning to change.
M, Riley, A, Anilionis
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