Results 191 to 200 of about 2,805,364 (358)

Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8

, 2010
Farnbacher M, Jahns T, Willrodt D, et al. Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8. BMC Genomics.
Haas, Rainer, Rainer Haas, Farnbacher, Max, Rieder Gabriele, Goesmann, Alexander ; https://orcid.org/, Farnbacher Max, Kurtz, Stefan, Rieder, Gabriele, Kurtz Stefan, Gabriele Rieder, Alexander Goesmann, Rolf Daniel, Daniel, Rolf, Willrodt Dirk, Dirk Willrodt, Max Farnbacher, Jahns, Thomas, Goesmann Alexander, Haas Rainer, Goesmann, Alexander, Thomas Jahns, Stefan Kurtz, Daniel Rolf, Willrodt, Dirk, Jahns Thomas, Gabriele, Rieder   +25 more
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

EDGAR: a software framework for the comparative analysis of prokaryotic genomes

, 2009
Blom J, Albaum S, Doppmeier D, et al. EDGAR: a software framework for the comparative analysis of prokaryotic genomes. BMC Bioinformatics. 2009;10(1): 154.Background:The introduction of next generation sequencing approaches has caused a rapid increase in
Blom, Jochen, Albaum, Stefan ; https://orcid.org/, Jochen Blom, Martha Zakrzewski, Goesmann, Alexander ; https://orcid.org/, Alfred Puhler, Pühler, Alfred ; https://orcid.org/, Zakrzewski, Martha, Doppmeier, Daniel, Vorhölter, Frank-Jörg, Stefan P Albaum, Daniel Doppmeier, Frank-Jorg Vorholter, Alexander Goesmann   +13 more
core   +1 more source

Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp

Applied and Environmental Microbiology, 2016
Min Xu, Yemin Wang, Zhilong Zhao, G. Gao, Sheng-Xiong Huang, Q. Kang, Xinyi He, Shuangjun Lin, Xiuhua Pang, Z. Deng, M. Tao   +10 more
semanticscholar   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

The entomopathogenic bacterial endosymbionts Xenorhabdus and Photorhabdus: convergent lifestyles from divergent genomes

, 2011
Members of the genus Xenorhabdus are entomopathogenic bacteria that associate with nematodes. The nematode-bacteria pair infects and kills insects, with both partners contributing to insect pathogenesis and the bacteria providing nutrition to the ...
Givaudan, Alain, Karina C. Krasomil-Osterfeld, Goldman, Barry S., Youngjin Park, Brian C. Tjaden, Latreille Phil, Kimberly N Cowles, Carolyn M Lipke, Slominski Kathryn, Jennifer J. Knack, Menard, Megan L., Jewell, Kelsea A., Slominski, Kathryn, Karina C Krasomil-Osterfeld, Bosong Xiang, Kelsea A Jewell, Park Youngjin, Carolyn M. Lipke, Norton, Stacie, Archna Bhasin, Darby Renneckar Sugar, Sugar, Darby Renneckar, Nydia Morales-Soto, Miller Nancy M., Latreille, Phil, Andersen Aaron W., Barry S. Goldman, Lipke, Carolyn M., Barbara A. Qurollo, Kukor, Ryan, Martens Eric C., Brachmann, Alexander O., Welch Roy D., Qurollo, Barbara A., Jewell Kelsea A., Barbazuk, Brad, Jennifer J Knack, Slater, Steven C., Holly Snyder, van der Hoeven, Ransome, Anne Lanois, John M. Chaston, John M Chaston, Xiang, Bosong, Alain Givaudan, Lu, Xiaojun, Chaston, John M., Knack, Jennifer J., Ogier, Jean-Claude, Drace Kevin, Renyi Liu, Dongjin Park, Suen, Garret, Andersen, Aaron W., Park, Dongjin, Kimberly N. Cowles, Nancy K. Leimgruber, Zoé Rouy, Krasomil-Osterfeld, Karina C., Roy D Welch, Darby Creg, Claudine Médigue, Xiang Bosong, Tran, Erin E. Herbert, Erin E Herbert Tran, Park Dongjin, Lu Xiaojun, Park, Youngjin, Jean-Claude Ogier, Roy D. Welch, Morales-Soto, Nydia, Steven C. Slater, Kevin Drace, Médigue, Claudine, de Léon, Limaris, Helge B. Bode, Xiaojun Lu, Leimgruber Nancy K., Edna Bode, Brad Barbazuk, Nancy M. Miller, Megan L. Menard, Welch, Roy D., Synder, Holly, Eric C Martens, Liu, Renyi, Barry S Goldman, Brad Goodner, Orchard Samantha S., Steven C Slater, Cowles Kimberly N., Rouy Zoé, Zijin Du, Forst Steven, Ransome van der Hoeven, Erin E. Herbert Tran, Bode, Edna, Suen Garret, Chaston John M., Liu Renyi, Gregory R. Richards, Knack Jennifer J., Wheeler, Cathy, Pradeep R Marri, Snyder, Holly, Samantha S Orchard, Drace, Kevin, Marri Pradeep R., Brian C Tjaden, Brachmann Alexander O., Marri, Pradeep R., Limaris de Léon, Goldman Barry S., Gaudriault Sophie, Garret Suen, Slominski Brad, Gaudriault, Sophie, Sugar Darby Renneckar, Charles E. Cowles, Forst, Steven, Sophie Gaudriault, Goodrich-Blair, Heidi, Kathryn Slominski, Lipke Carolyn M., Heidi Goodrich-Blair, Gaudriault, Sophie, S., Cathy Wheeler, Charles E Cowles, Martens, Eric C., Sarah L Tucker, Givaudan Alain, Goodrich-Blair Heidi, Richards, Gregory R., Gregory R Richards, Aaron W Andersen, Miller, Nancy M., Phil Latreille, Ryan Kukor, Qurollo Barbara A., Barbazuk Brad, Tucker Sarah L., Cowles Charles E., Cowles, Kimberly N., Barbara A Qurollo, Lanois Anne, Snyder Holly, Darby, Creg, Léon, Limaris de, Bhasin Archna, Pradeep R. Marri, Leimgruber, Nancy K., Bhasin, Archna, Nancy M Miller, Brad Slominski, Bode, Helge Björn, Cowles, Charles E., Bode Edna, Slominski, Brad, Tjaden, Brian C., Kukor Ryan, Stacie Norton, Alexander O. Brachmann, Rouy, Zoé, Slater Steven C., Eric C. Martens, Lanois, Anne, Steven Forst, Hoeven, Ransome van der, Bode Helge B., Creg Darby, Aaron W. Andersen, Médigue Claudine, van der Hoeven Ransome, Alexander O Brachmann, Nancy K Leimgruber, Krasomil-Osterfeld Karina C., Menard Megan L., Kelsea A. Jewell, Sarah L. Tucker, Renneckar Sugar, Darby, Wheeler Cathy, Goodner, Brad, Morales-Soto Nydia, Goodner Brad, Bode, Helge B., Megan L Menard, Richards Gregory R., Norton Stacie, Helge B Bode, Du, Zijin, Orchard, Samantha S., de Léon Limaris, Tucker, Sarah L., Brachmann, Alexander Oliver, Du Zijin, Herbert Tran Erin E., Ogier Jean-Claude, Samantha S. Orchard, Tjaden Brian C.   +198 more
core   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Evolutionary trajectory of white spot syndrome virus (WSSV) genome shrinkage during spread in Asia

, 2010
Background - White spot syndrome virus (WSSV) is the sole member of the novel Nimaviridae family, and the source of major economic problems in shrimp aquaculture.
Bui Thi Minh Dieu, Zwart, Mark P., Lia Hemerik, Hemerik, L., Mark P. Zwart, Just M. Vlak, Mark P Zwart, Dieu, Bui Thi Minh, Vlak, J.M., Hemerik, Lia, Just M Vlak, Zwart, M.P., Vlak, Just M.   +12 more
core   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source