Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies. [PDF]
BACKGROUND: The amplification of bacterial RNA is required if complex host-pathogen interactions are to be studied where the recovery of bacterial RNA is limited.
Laing Ken +15 more
core +1 more source
Coxiella burnetii is the causative agent of the zoonotic disease Q fever. To date, the lipopolysaccharide (LPS) is the only defined and characterized virulence determinant of C. burnetii. In this study, proteome profiles of C. burnetii Nine Mile phase I (
Jiri Dresler +8 more
doaj +1 more source
Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. [PDF]
BACKGROUND: Human and animal health is constantly under threat by emerging pathogens that have recently acquired genetic determinants that enhance their survival, transmissibility and virulence.
Oyston, Petra C. F. +38 more
core +1 more source
Inter-species horizontal transfer resulting in core-genome and niche-adaptive variation within Helicobacter pylori [PDF]
Background Horizontal gene transfer is central to evolution in most bacterial species. The detection of exchanged regions is often based upon analysis of compositional characteristics and their comparison to the organism as a whole.
Boonmee, P +17 more
core +1 more source
Consistent Metagenome-Derived Metrics Verify and Delineate Bacterial Species Boundaries
Longstanding questions relate to the existence of naturally distinct bacterial species and genetic approaches to distinguish them. Bacterial genomes in public databases form distinct groups, but these databases are subject to isolation and deposition ...
Matthew R. Olm +5 more
doaj +3 more sources
Whole genome sequencing has become a powerful tool in modern microbiology. Especially bacterial genomes are sequenced in high numbers. Whole genome sequencing is not only used in research projects, but also in surveillance projects and outbreak ...
Bo Segerman, Bo Segerman
doaj +1 more source
Genome sequence of the pattern forming
Background The pattern-forming bacterium Paenibacillus vortex is notable for its advanced social behavior, which is reflected in development of colonies with highly intricate architectures.
Colin Ingham +47 more
core +1 more source
Genome-wide detection of spontaneous chromosomal rearrangements in bacteria. [PDF]
Genome rearrangements have important effects on bacterial phenotypes and influence the evolution of bacterial genomes. Conventional strategies for characterizing rearrangements in bacterial genomes rely on comparisons of sequenced genomes from related ...
Song Sun +4 more
doaj +1 more source
Identification of DNA motifs implicated in maintenance of bacterial core genomes by predictive modeling [PDF]
Bacterial biodiversity at the species level, in terms of gene acquisition or loss, is so immense that it raises the question of how essential chromosomal regions are spared from uncontrolled rearrangements.
El Karoui, Meriem +20 more
core +2 more sources
Genomic Arrangement of Regulons in Bacterial Genomes
Regulons, as groups of transcriptionally co-regulated operons, are the basic units of cellular response systems in bacterial cells. While the concept has been long and widely used in bacterial studies since it was first proposed in 1964, very little is known about how its component operons are arranged in a bacterial genome.
Han Zhang +3 more
openaire +4 more sources

