Results 31 to 40 of about 2,805,364 (358)

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential

open access: yesGenome Medicine, 2020
Background Plasmodium falciparum (Pf) whole-organism sporozoite vaccines have been shown to provide significant protection against controlled human malaria infection (CHMI) in clinical trials.
Kara A. Moser   +33 more
doaj   +1 more source

Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads

open access: yesbioRxiv, 2016
The Illumina DNA sequencing platform generates accurate but short reads, which can be used to produce accurate but fragmented genome assemblies. Pacific Biosciences and Oxford Nanopore Technologies DNA sequencing platforms generate long reads that can ...
R. Wick, L. Judd, C. Gorrie, K. Holt
semanticscholar   +1 more source

fIDBAC: A Platform for Fast Bacterial Genome Identification and Typing

open access: yesFrontiers in Microbiology, 2021
To study the contamination of microorganisms in the food industry, pharmaceutical industry, clinical diagnosis, or bacterial taxonomy, accurate identification of species is a key starting point of further investigation.
Qian Liang   +13 more
doaj   +1 more source

Automated design of bacterial genome sequences [PDF]

open access: yes, 2013
Background: Organisms have evolved ways of regulating transcription to better adapt to varying environments. Could the current functional genomics data and models support the possibility of engineering a genome with completely rearranged gene ...
Javier Carrera   +3 more
core   +1 more source

Bacterial Nomenclature in the Era of Genomics [PDF]

open access: yesNew Microbes and New Infections, 2021
The remarkable success of taxonomic discovery, powered by culturomics, genomics and metagenomics, creates a pressing need for new bacterial names, while holding a mirror up to the slow pace of change in bacterial nomenclature. Here, I take a fresh look at bacterial nomenclature, exploring how we might create a system fit for the age of genomics ...
openaire   +4 more sources

Diversity and role of plasmids in adaptation of bacteria inhabiting the Lubin copper mine in Poland, an environment rich in heavy metals

open access: yesFrontiers in Microbiology, 2015
The Lubin underground mine, is one of three mining divisions in the Lubin-Glogow Copper District in Lower Silesia province (Poland). It is the source of polymetallic ore that is rich in copper, silver and several heavy metals.
Lukasz eDziewit   +8 more
doaj   +1 more source

Bacterial epidemiology and biology--lessons from genome sequencing. [PDF]

open access: yes, 2011
Next-generation sequencing has ushered in a new era of microbial genomics, enabling the detailed historical and geographical tracing of bacteria.
Wren, Brendan W   +3 more
core   +1 more source

Genomics and Bacterial Pathogenesis [PDF]

open access: yesEmerging Infectious Diseases, 2000
Whole-genome sequencing is transforming the study of pathogenic bacteria. Searches for single virulence genes can now be performed on a genomewide scale by a variety of computer and genetic techniques. These techniques are discussed to provide a perspective on the developing field of genomics.
openaire   +3 more sources

A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of life

open access: yesNature Biotechnology, 2018
Taxonomy is an organizing principle of biology and is ideally based on evolutionary relationships among organisms. Development of a robust bacterial taxonomy has been hindered by an inability to obtain most bacteria in pure culture and, to a lesser ...
Donovan H. Parks   +6 more
semanticscholar   +1 more source

GTDB-Tk v2: memory friendly classification with the genome taxonomy database

open access: yesbioRxiv, 2022
The Genome Taxonomy Database (GTDB) and associated taxonomic classification toolkit (GTDB-Tk) have been widely adopted by the microbiology community.
Pierre-Alain Chaumeil   +3 more
semanticscholar   +1 more source

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