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SIMBA: a web tool for managing bacterial genome assembly generated by Ion PGM sequencing technology [PDF]
Background The evolution of Next-Generation Sequencing (NGS) has considerably reduced the cost per sequenced-base, allowing a significant rise of sequencing projects, mainly in prokaryotes. However, the range of available NGS platforms requires different
Aguiar, Edgar L. +13 more
core +3 more sources
Coxiella burnetii is the causative agent of the zoonotic disease Q fever. To date, the lipopolysaccharide (LPS) is the only defined and characterized virulence determinant of C. burnetii. In this study, proteome profiles of C. burnetii Nine Mile phase I (
Jiri Dresler +8 more
doaj +1 more source
Genome sequence of the pattern forming Paenibacillus vortex bacterium reveals potential for thriving in complex environments [PDF]
Background: The pattern-forming bacterium Paenibacillus vortex is notable for its advanced social behavior, which is reflected in development of colonies with highly intricate architectures.
Sirota-Madi, A. +15 more
core +3 more sources
Consistent Metagenome-Derived Metrics Verify and Delineate Bacterial Species Boundaries
Longstanding questions relate to the existence of naturally distinct bacterial species and genetic approaches to distinguish them. Bacterial genomes in public databases form distinct groups, but these databases are subject to isolation and deposition ...
Matthew R. Olm +5 more
doaj +3 more sources
Genomic Features Of A Bumble Bee Symbiont Reflect Its Host Environment [PDF]
Here, we report the genome of one gammaproteobacterial member of the gut microbiota, for which we propose the name >Candidatus Schmidhempelia bombi,> that was inadvertently sequenced alongside the genome of its host, the bumble bee, Bombus impatiens ...
Koch, Hauke +4 more
core +1 more source
Bacterial Genomes: Habitat Specificity and Uncharted Organisms [PDF]
The capability and speed in generating genomic data have increased profoundly since the release of the draft human genome in 2000. Additionally, sequencing costs have continued to plummet as the next generation of highly efficient sequencing technologies (next-generation sequencing) became available and commercial facilities promote market competition.
Dini-Andreote, Francisco +4 more
openaire +3 more sources
Genomics and Bacterial Pathogenesis [PDF]
Whole-genome sequencing is transforming the study of pathogenic bacteria. Searches for single virulence genes can now be performed on a genomewide scale by a variety of computer and genetic techniques. These techniques are discussed to provide a perspective on the developing field of genomics.
openaire +3 more sources
Whole genome sequencing has become a powerful tool in modern microbiology. Especially bacterial genomes are sequenced in high numbers. Whole genome sequencing is not only used in research projects, but also in surveillance projects and outbreak ...
Bo Segerman, Bo Segerman
doaj +1 more source
Genome-wide detection of spontaneous chromosomal rearrangements in bacteria. [PDF]
Genome rearrangements have important effects on bacterial phenotypes and influence the evolution of bacterial genomes. Conventional strategies for characterizing rearrangements in bacterial genomes rely on comparisons of sequenced genomes from related ...
Song Sun +4 more
doaj +1 more source
Osmotic pressure: resisting or promoting DNA ejection from phage [PDF]
Recent in vitro experiments have shown that DNA ejection from bacteriophage can be partially stopped by surrounding osmotic pressure when ejected DNA is digested by DNase I on the course of ejection.
Castelnovo, Martin +4 more
core +3 more sources

