Results 11 to 20 of about 449,272 (264)

The Evolution of Bacterial Genome Architecture [PDF]

open access: yesFrontiers in Genetics, 2017
The genome architecture of bacteria and eukaryotes evolves in opposite directions when subject to genetic drift, a difference that can be ascribed to the fact that bacteria exhibit a mutational bias that deletes superfluous sequences, whereas eukaryotes ...
Louis-Marie Bobay, Howard Ochman
doaj   +3 more sources

Bacterial genomics [PDF]

open access: yesFEMS Microbiology Reviews, 1994
During the last decade, great advances have been made in the study of bacterial genomes which is perhaps better described by the term bacterial genomics. The application of powerful techniques, such as pulsed-field gel electrophoresis of macro-restriction fragments of genomic DNA, has freed the characterisation of the chromosomes of many bacteria from ...
S T, Cole, I, Saint Girons
  +6 more sources

Bacterial Genome Instability [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2014
SUMMARY Bacterial genomes are remarkably stable from one generation to the next but are plastic on an evolutionary time scale, substantially shaped by horizontal gene transfer, genome rearrangement, and the activities of mobile DNA elements. This implies the existence of a delicate balance between the maintenance of genome stability and the ...
Elise, Darmon, David R F, Leach
openaire   +2 more sources

Bacterial Genomics and Epidemiology

open access: yesMicroorganisms, 2023
Innovative technologies for Whole-Genome Sequencing (WGS) help to improve our understanding of the epidemiology and pathogenesis of bacterial infectious diseases and are becoming affordable for most microbiological laboratories [...]
Javier Garaizar, Lorena Laorden
openaire   +4 more sources

The layout of a bacterial genome [PDF]

open access: yesFEBS Letters, 2012
Recently the mismatch between our newly acquired capacity to synthetize DNA at genome scale, and our low capacity to design ab initio a functional genome has become conspicuous. This essay gathers a variety of constraints that globally shape natural genomes, with a focus on eubacteria.
Képès, François   +5 more
openaire   +2 more sources

Genomics and Bacterial Pathogenesis [PDF]

open access: yesEmerging Infectious Diseases, 2000
Whole-genome sequencing is transforming the study of pathogenic bacteria. Searches for single virulence genes can now be performed on a genomewide scale by a variety of computer and genetic techniques. These techniques are discussed to provide a perspective on the developing field of genomics.
openaire   +3 more sources

Bacterial genome mapper: A comparative bacterial genome mapping tool [PDF]

open access: yesBioinformation, 2012
Recently, next generation sequencing (NGS) technologies have led to a revolutionary increase in sequencing speed and costefficacy. Consequently, a vast number of contigs from many recently sequenced bacterial genomes remain to be accurately mapped and annotated, requiring the development of more convenient bioinformatics programs.
Lee, Kang Seon   +12 more
openaire   +2 more sources

Bacterial Nomenclature in the Era of Genomics [PDF]

open access: yesNew Microbes and New Infections, 2021
The remarkable success of taxonomic discovery, powered by culturomics, genomics and metagenomics, creates a pressing need for new bacterial names, while holding a mirror up to the slow pace of change in bacterial nomenclature. Here, I take a fresh look at bacterial nomenclature, exploring how we might create a system fit for the age of genomics ...
openaire   +4 more sources

Diversity and role of plasmids in adaptation of bacteria inhabiting the Lubin copper mine in Poland, an environment rich in heavy metals

open access: yesFrontiers in Microbiology, 2015
The Lubin underground mine, is one of three mining divisions in the Lubin-Glogow Copper District in Lower Silesia province (Poland). It is the source of polymetallic ore that is rich in copper, silver and several heavy metals.
Lukasz eDziewit   +8 more
doaj   +1 more source

Genome-wide insights into population structure and host specificity of Campylobacter jejuni

open access: yesScientific Reports, 2021
The zoonotic pathogen Campylobacter jejuni is among the leading causes of foodborne diseases worldwide. While C. jejuni colonises many wild animals and livestock, persistence mechanisms enabling the bacterium to adapt to host species' guts are not fully ...
Lennard Epping   +11 more
doaj   +1 more source

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