Results 11 to 20 of about 2,805,364 (358)
The Evolution of Bacterial Genome Architecture [PDF]
Frontiers in Genetics, 2017 The genome architecture of bacteria and eukaryotes evolves in opposite directions when subject to genetic drift, a difference that can be ascribed to the fact that bacteria exhibit a mutational bias that deletes superfluous sequences, whereas eukaryotes ...
Louis-Marie Bobay, Howard Ochman
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Assembling the perfect bacterial genome using Oxford Nanopore and Illumina sequencing
PLoS Computational Biology, 2023 A perfect bacterial genome assembly is one where the assembled sequence is an exact match for the organism’s genome—each replicon sequence is complete and contains no errors. While this has been difficult to achieve in the past, improvements in long-read
Ryan R. Wick +2 more
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Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops [PDF]
BMC Bioinformatics, 2005 Background Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to address questions about bacterial genome evolution, a task that requires ...
Gendrault-Jacquemard A +6 more
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Nature Communications, 2023 Bacterial gene repertoires reflect adaptive strategies, contribute to ecosystem functioning and are limited by genome size. However, gene functional diversity does not necessarily correlate with taxonomic diversity because average genome size may vary by
Cong Wang +6 more
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FEMS Microbiology Reviews, 1994 During the last decade, great advances have been made in the study of bacterial genomes which is perhaps better described by the term bacterial genomics. The application of powerful techniques, such as pulsed-field gel electrophoresis of macro-restriction fragments of genomic DNA, has freed the characterisation of the chromosomes of many bacteria from ...
S T, Cole, I, Saint Girons
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Nucleic Acids Res., 2021 The Genome Taxonomy Database (GTDB; https://gtdb.ecogenomic.org) provides a phylogenetically consistent and rank normalized genome-based taxonomy for prokaryotic genomes sourced from the NCBI Assembly database.
Donovan H. Parks +5 more
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Polypolish: Short-read polishing of long-read bacterial genome assemblies
bioRxiv, 2021 Long-read-only bacterial genome assemblies usually contain residual errors, most commonly homopolymer-length errors. Short-read polishing tools can use short reads to fix these errors, but most rely on short-read alignment which is unreliable in repeat ...
R. Wick, K. Holt
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mSystems, 2021 Bacillus subtilis produces a wide range of secondary metabolites providing diverse plant growth-promoting and biocontrol abilities. These secondary metabolites include nonribosomal peptides with strong antimicrobial properties, causing either cell lysis,
Heiko T. Kiesewalter +10 more
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Bacterial Genome Instability [PDF]
Microbiology and Molecular Biology Reviews, 2014 SUMMARY Bacterial genomes are remarkably stable from one generation to the next but are plastic on an evolutionary time scale, substantially shaped by horizontal gene transfer, genome rearrangement, and the activities of mobile DNA elements. This implies the existence of a delicate balance between the maintenance of genome stability and the ...
Elise, Darmon, David R F, Leach
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BMC Genomics, 2023 Background Bacterial epidemiology needs to understand the spread and dissemination of strains in a One Health context. This is important for highly pathogenic bacteria such as Bacillus anthracis, Brucella species, and Francisella tularensis. Whole genome
Jörg Linde +6 more
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