Results 91 to 98 of about 99 (98)
Aging Cell, EarlyView.The overexpression of gst‐35, the mammalian orthologous genes GSTA1, GSTA2, and GSTA3, induces lysosomal dysfunction through the genes pmk‐1 and skr in C. elegans. This overexpression not only promotes an in vivo inflammatory response and accumulation of reactive oxygen species but also significantly shortens the nematode lifespan; inhibits its ...
Yehui Gao +8 more
wiley +1 more source
Phosphorylation of an RNA‐Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging
Aging Cell, EarlyView.Evolutionary conserved Hippo/Mst1 signaling non‐canonically regulates the stability of mRNAs through directly phosphorylating a subset of RNA binding proteins to stabilize lipolytic mRNAs. Hpo pathway contributes to the regulation of Drosophila lifespan by modulating the expression and activity of Me31b/RCK, which subsequently affects mRNA levels of ...
Eunbyul Yeom +26 more
wiley +1 more source
Animal Conservation, EarlyView.Environmental DNA is a powerful tool for simultaneous detection of rare species and their pathogens. We confirmed the presence of Atelopus at multiple sampling locations and found that the concentration of the amphibian pathogen Bd in eDNA samples was correlated with stream characteristics and the pathogen load of the amphibian community.
Jamie Voyles +6 more
wiley +1 more source
Potential of alternative control of leaf‐cutting ants using essential oils: A systematic review
Agricultural and Forest Entomology, EarlyView.Abstract Leaf‐cutting ants (LCAs) are abundant and cause considerable damage to agricultural and forest crops in the Neotropical region and are commonly controlled using sulfluramid‐based ant baits. However, this active ingredient is a precursor of perfluorooctane sulfonic acid (PFOS), a persistent, human‐made pollutant that poses serious environmental
Heloisa S. S. Pinheiro +9 more
wiley +1 more source
Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China
British Journal of Pharmacology, EarlyView.Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang +5 more
wiley +1 more source
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison +15 more
wiley +1 more source
Biodiversity in mountain soils above the treeline
Biological Reviews, EarlyView.ABSTRACT Biological diversity in mountain ecosystems has been increasingly studied over the last decade. This is also the case for mountain soils, but no study to date has provided an overall synthesis of the current state of knowledge. Here we fill this gap with a first global analysis of published research on cryptogams, microorganisms, and fauna in ...
Nadine Praeg +36 more
wiley +1 more source
Biological Reviews, EarlyView.ABSTRACT From blood‐sucking lice and food‐stealing gulls to pandemic‐inducing viruses and egg‐eating snakes: parasites and predators are ubiquitous in shaping ecology and evolution. Fundamental to these interactions is the way in which parasites and predators choose their victim. Here, I argue that a trade‐off between host quality and vulnerability can
Mairenn C. Attwood
wiley +1 more source