Results 91 to 100 of about 457,413 (290)

A broad distribution of the alternative oxidase in microsporidian parasites [PDF]

, 2010
Microsporidia are a group of obligate intracellular parasitic eukaryotes that were considered to be amitochondriate until the recent discovery of highly reduced mitochondrial organelles called mitosomes. Analysis of the complete genome of Encephalitozoon
A Atteia, A Stechmann, AD Tsaousis, AE McDonald, AL Moore, AL Moore, AL Umbach, Anthony L. Moore, AV Goldberg, BA Williams, BA Williams, BA Williams, Bryony A. P. Williams, C Affourtit, C Larsson, C Nihei, Catherine Elliot, CH Slamovits, CR Vossbrinck, CW Roberts, DA Berthold, DE Akiyoshi, E Weidner, ES Didier, ES Didier, F Thomarat, GC Vanlerberghe, GV Beznoussenko, I Small, JA Eisen, JD Thompson, JP Huelsenbeck, K Kita, Kiyoshi Kita, Lena Burri, M Chaudhuri, M Nina, MD Katinka, MG Claros, MJ Gardner, MS Albury, MS Albury, MS Albury, N Minagawa, O Emanuelsson, P Stenmark, Patricia J. Johnson, Patrick J. Keeling, PG Crichton, PJ Didier, PJ Keeling, R George, RP Hirt, RS Cornman, S Guindon, SJ Qureshi, T Joseph-Horne, T Suzuki, TA Richards, TD Edlind, TE Elthon, TM Keane, W Jarmuszkiewicz, Y Fukai, Yasutoshi Kido   +64 more
core   +4 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Oxygen Glucose Deprivation Induced Prosurvival Autophagy Is Insufficient to Rescue Endothelial Function

Frontiers in Physiology, 2020
Endothelial dysfunction, referring to a disturbance in the vascular homeostasis, has been implicated in many disease conditions including ischemic/reperfusion injury and atherosclerosis.
Venkateswaran Natarajan, Tania Mah, Chen Peishi, Shu Yi Tan, Ritu Chawla, Thiruma Valavan Arumugam, Adaikalavan Ramasamy, Karthik Mallilankaraman, Karthik Mallilankaraman   +8 more
doaj   +1 more source

Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]

, 2016
The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R., Howe, Christopher J., Nisbet, R. Ellen R.   +2 more
core   +4 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

The complete mitochondrial genome of Yarrowia lipolytica [PDF]

, 2008
We here report the complete nucleotide sequence of the 47.9 kb mitochondrial (mt) genome from the obligate aerobic yeast Yarrowia lipolytica.
Brandt, Ulrich, Casaregola, Serge, Durstewitz, Gregor, Gaillardin, Claude, Kerscher, Stefan   +4 more
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

MitoIMP: A Computational Framework for Imputation of Missing Data in Low-Coverage Human Mitochondrial Genome

Bioinformatics and Biology Insights, 2019
The incompleteness of partial human mitochondrial genome sequences makes it difficult to perform relevant comparisons among multiple resources. To deal with this issue, we propose a computational framework for deducing missing nucleotides in the human ...
Koji Ishiya, Fuzuki Mizuno, Li Wang, Shintaroh Ueda   +3 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Comparative analysis of chloroplast and mitochondrial genomes of sweet potato provides evidence of gene transfer

Scientific Reports
The increasing number of plant mitochondrial DNA genomes (mtDNA) sequenced reveals the extent of transfer from both chloroplast DNA genomes (cpDNA) and nuclear DNA genomes (nDNA).
GuoLiang Li, Hong Zhang, Zhaomiao Lin, Huawei Li, Guochun Xu, Yongqing Xu, Rongchang Ji, Wenbin Luo, Yongxiang Qiu, Sixin Qiu, Hao Tang   +10 more
doaj   +1 more source