Results 51 to 60 of about 246,081 (272)
Mitochondrial genomes as living ‘fossils’ [PDF]
BMC Biology, 2013 The huge variation between mitochondrial genomes makes untangling their evolutionary histories difficult. Richardson et al. report on the remarkably unaltered 'fossil' genome of the tulip tree, giving us many clues as to how the mitochondrial genomes of flowering plants have evolved over the last 150 million years, and raising questions about how such ...
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Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Advanced Genetics, 2022 We are living in the era of genome editing. Nowadays, targeted editing of the plant nuclear DNA is prevalent in basic biological research and crop improvement since its first establishment a decade ago.
Jinghua Yang +4 more
doaj +1 more source
Intraspecific Comparative Genomics of Candida albicans Mitochondria Reveals Non-Coding Regions Under Neutral Evolution [PDF]
, 2012 The opportunistic fungal pathogen Candida albicans causes serious hematogenic hospital acquired candidiasis with worldwide impact on public health. Because of its importance as a nosocomial etiologic agent, C. albicans genome has been largely studied to identify intraspecific variation and several typing methods have been developed to distinguish ...
arxiv +1 more source
Progress in the definition of a reference human mitochondrial proteome [PDF]
Proteomics 3 (02/2003) 157-67, 2006 Owing to the complexity of higher eukaryotic cells, a complete proteome is likely to be very difficult to achieve. However, advantage can be taken of the cell compartmentalization to build organelle proteomes, which can moreover be viewed as specialized tools to study specifically the biology and "physiology" of the target organelle. Within this frame,
arxiv +1 more source
The Mitochondrial Genome of Toxocara canis
PLoS Neglected Tropical Diseases, 2008 Toxocara canis (Ascaridida: Nematoda), which parasitizes (at the adult stage) the small intestine of canids, can be transmitted to a range of other mammals, including humans, and can cause the disease toxocariasis. Despite its significance as a pathogen, the genetics, epidemiology and biology of this parasite remain poorly understood.
Jex, AR +4 more
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Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Complete mitochondrial DNA analysis of Hydrotaea ignava (Insecta, Diptera, Muscidae)
Mitochondrial DNA. Part B. Resources, 2017 The complete mitochondrial genome sequenced and analyzed from a black garbage fly, Hydrotaea ignava which is critically important species for forensic investigations. The size of mitochondrial genome is 17,026 bp with 40.8% A, 11.2% C, 8.2% G and 39.8% T
Mustafa Zafer Karagozlu +3 more
doaj +1 more source
BMC Genomics, 2012 Background Plant mitochondrial genome has unique features such as large size, frequent recombination and incorporation of foreign DNA. Cytoplasmic male sterility (CMS) is caused by rearrangement of the mitochondrial genome, and a novel chimeric open ...
Tanaka Yoshiyuki +4 more
doaj +1 more source
Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome [PDF]
Oxidative Medicine and Cellular Longevity, 2017 Mitochondria preserve very complex and distinctively unique machinery to maintain and express the content of mitochondrial DNA (mtDNA). Similar to chromosomes, mtDNA is packaged into discrete mtDNA‐protein complexes referred to as a nucleoid. In addition to its role as a mtDNA shield, over 50 nucleoid‐associated proteins play roles in mtDNA maintenance
Sung Ryul Lee, Jin Han
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