Results 61 to 70 of about 457,413 (290)

The Mitochondrial Genome of Toxocara canis

PLoS Neglected Tropical Diseases, 2008
Toxocara canis (Ascaridida: Nematoda), which parasitizes (at the adult stage) the small intestine of canids, can be transmitted to a range of other mammals, including humans, and can cause the disease toxocariasis. Despite its significance as a pathogen, the genetics, epidemiology and biology of this parasite remain poorly understood.
Jex, AR, Waeschenbach, A, Littlewood, DTJ, Hu, M, Gasser, RB   +4 more
openaire   +6 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

A fragmented metazoan organellar genome [PDF]

, 2008
Background: Animal mitochondrial (mt) genomes are characteristically circular molecules of ~16–20 kb. Medusozoa (Cnidaria excluding Anthozoa) are exceptional in that their mt genomes are linear and sometimes subdivided into two to presumably four ...
Erpenbeck, Dirk, Voigt, Oliver, Wörheide, Gert   +2 more
core   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Evolutionary Analysis of Mitogenomes from Parasitic and Free-Living Flatworms [PDF]

, 2015
Copyright: © 2015 Solà et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
A Marín, A Necşulea, AR Wey-Fabrizius, C Gissi, CM Barr, Cristina Frías-López, D Laslett, D. Timothy J. Littlewood, DC Shields, DS Lawrie, E Solà, Eduard Solà, ERM Tillier, F Abascal, F Wright, G Bernardi, H Chen, H Yamasaki, H-K Jeon, Hector Escriva, I Ruiz-Trillo, J Boore, J Zhang, Julio Rozas, JWO Ballard, JWO Ballard, L Bromham, LR Castro, M Bernt, M Dowton, M Nakao, M Riutort, M Sakai, M Stöck, M Weber, M Woolfit, M Álvarez-Presas, M Álvarez-Presas, Marta Riutort, Marta Álvarez-Presas, MJ Telford, MP Francino, NT Perna, P Chomczynski, P Schattner, PM Sharp, R Schmieder, R Sluys, RD Page, S Breton, S Kang, S Wei, SK Wyman, SM Huse, T Huyse, T Huyse, T Le, T Le, TH Le, Y Bessho, Y Bessho, Y-P Poh   +61 more
core   +3 more sources

Mitochondrial genomes as living ‘fossils’ [PDF]

BMC Biology, 2013
The huge variation between mitochondrial genomes makes untangling their evolutionary histories difficult. Richardson et al. report on the remarkably unaltered 'fossil' genome of the tulip tree, giving us many clues as to how the mitochondrial genomes of flowering plants have evolved over the last 150 million years, and raising questions about how such ...
openaire   +2 more sources

Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome [PDF]

Oxidative Medicine and Cellular Longevity, 2017
Mitochondria preserve very complex and distinctively unique machinery to maintain and express the content of mitochondrial DNA (mtDNA). Similar to chromosomes, mtDNA is packaged into discrete mtDNA‐protein complexes referred to as a nucleoid. In addition to its role as a mtDNA shield, over 50 nucleoid‐associated proteins play roles in mtDNA maintenance
Sung Ryul Lee, Jin Han
openaire   +3 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Characterization and phylogenetic analysis of the complete mitochondrial genome of Clavulina sp. (Cantharellales: Clavulinaceae)

Mitochondrial DNA. Part B. Resources, 2020
In this study, the complete mitochondrial genome of Clavulina sp. was sequenced and assembled. The complete mitochondrial genome of Clavulina sp. contains 20 protein-coding (PCG) genes, 2 ribosomal RNA (rRNA) genes, and 25 transfer RNA (tRNA) genes.
Maoling Tan, Gang Zhao
doaj   +1 more source

The Mitochondrial Genome of Baylisascaris procyonis

PLoS ONE, 2011
Baylisascaris procyonis (Nematoda: Ascaridida), an intestinal nematode of raccoons, is emerging as an important helminthic zoonosis due to serious or fatal larval migrans in animals and humans. Despite its significant veterinary and public health impact, the epidemiology, molecular ecology and population genetics of this parasite remain largely ...
Jiabo Deng, Yue Xie, Xiaobin Gu, Guangyou Yang, Ning Yan, Deying Yang, Jingchao Lan, Guiying Hao, Zhihe Zhang, Huaming Nie, Xuerong Peng, Yan Fu, Lili Niu, Chengdong Wang, Shuxian Wang, Qiang Wang   +15 more
openaire   +5 more sources