Results 131 to 140 of about 1,052,313 (231)

A unique dual activity amino acid hydroxylase in Toxoplasma gondii.

open access: yesPLoS ONE, 2009
The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes encoding tyrosine hydroxylase; that produces L-DOPA. The encoded enzymes metabolize phenylalanine as well as tyrosine with substrate preference for tyrosine.
Elizabeth A Gaskell   +4 more
doaj   +1 more source

Within-Species Genomic Variation and Variable Patterns of Recombination in the Tetracycline Producer Streptomyces rimosus

open access: yesFrontiers in Microbiology, 2019
Streptomyces rimosus is best known as the primary source of the tetracycline class of antibiotics, most notably oxytetracycline, which have been widely used against many gram-positive and gram-negative pathogens and protozoan parasites.
Cooper J. Park, Cheryl P. Andam
doaj   +1 more source

The impact of mutation and gene conversion on the local diversification of antigen genes in African trypanosomes [PDF]

open access: yes, 2012
Patterns of genetic diversity in parasite antigen gene families hold important information about their potential to generate antigenic variation within and between hosts.
Awadalla   +12 more
core   +1 more source

Expression of the C-terminal family 22 carbohydratebinding module of xylanase 10B of Clostridium themocellum in tobacco plant [PDF]

open access: yes, 2009
Carbohydrate-binding modules have been shown to alter plant cell wall structural architecture. Hence, they have the potential application of being used to engineer the plant to produce tailor-made natural fibers in the cell wall.
Obembe, Olawole O.
core   +2 more sources

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei.

open access: yesPLoS Pathogens, 2017
Mitochondria cannot form de novo but require mechanisms that mediate their inheritance to daughter cells. The parasitic protozoan Trypanosoma brucei has a single mitochondrion with a single-unit genome that is physically connected across the two ...
Sandro Käser   +10 more
doaj   +1 more source

Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification

open access: yesmBio, 2018
Protozoan parasites of the genus Leishmania cause severe human and veterinary diseases worldwide, termed leishmaniases. A hallmark of Leishmania biology is its capacity to adapt to a variety of unpredictable fluctuations inside its human host, notably ...
G. Bussotti   +29 more
semanticscholar   +1 more source

Host genome integration and giant virus-induced reactivation of the virophage mavirus

open access: yesNature, 2016
Endogenous viral elements are increasingly found in eukaryotic genomes, yet little is known about their origins, dynamics, or function. Here we provide a compelling example of a DNA virus that readily integrates into a eukaryotic genome where it acts as ...
M. Fischer, T. Hackl
semanticscholar   +1 more source

Proteomic analysis of the ventral disc of Giardia lamblia

open access: yesBMC Research Notes, 2012
Background Giardia lamblia is a multiflagellated protozoan that inhabits the small intestine of vertebrates, causing giardiasis. To colonize the small intestine, the trophozoites form of the parasite remains attached to intestinal epithelial cells by ...
Lourenço Daniela   +5 more
doaj   +1 more source

The first Cyclospora cayetanensis lineage A genome from an isolate from Mexico

open access: yesBMC Genomics
Background Cyclospora cayetanensis is a protozoan parasite that causes intestinal illness in humans worldwide. Despite its global distribution, most genomic data for C.
Monica Santin   +4 more
doaj   +1 more source

Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages.

open access: yesPLoS Pathogens, 2014
Infection of macrophages by the intracellular protozoan Leishmania leads to down-regulation of a number of macrophage innate host defense mechanisms, thereby allowing parasite survival and replication.
Alexandra K Marr   +5 more
doaj   +1 more source

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