Results 1 to 10 of about 113,128 (245)

Pomegranate (Punica granatum) Peel Inhibits the In Vitro and In Vivo Growth of Piroplasm Parasites

Journal of Parasitology Research, 2022
Pomegranate (Punica granatum) peel has seen a rapid surge in attention as a medical and nutritional product over the last decade. The impact of pomegranate peel methanolic extract monotherapy and combination therapy on the in vitro growth of Babesia (B.)
Rasha Eltaysh, Mohamed Abdo Rizk, Bassem Elmishmishy, Shimaa Abd El-Salam El-Sayed, Khaled Abouelnasr, Ikuo Igarashi   +5 more
doaj   +1 more source

Effect of α-tocopheryloxy acetic acid, a vitamin E derivative mitocan, on the experimental infection of mice with Plasmodium yoelii

Malaria Journal, 2021
Background Malaria parasites are known to be vulnerable to oxidative stress. In this study, the effects of the administration of α-tocopheryloxy acetic acid (α-TEA), which is a vitamin E analogue mitocan, on Plasmodium yoelii infection in mice were ...
Kasumi Kawamura, Aiko Kume, Rika Umemiya-Shirafuji, Shunji Kasai, Hiroshi Suzuki   +4 more
doaj   +1 more source

Molecular Detection and Phylogenetic Analyses of Babesia spp. and Theileria spp. in Livestock in Bangladesh

Microorganisms, 2023
Piroplasmosis, caused by Babesia spp. and Theileria spp., poses significant constraints for livestock production and upgradation in Bangladesh. Besides examining blood smears, few molecular reports are available from some selected areas in the country ...
Uday Kumar Mohanta, Boniface Chikufenji, Eloiza May Galon, Shengwei Ji, Zhuowei Ma, Shimaa Abd El-Salam El-Sayed, Aaron Edmond Ringo, Thanh Thom Do, Xuenan Xuan   +8 more
doaj   +1 more source

Inhibitory effect of naphthoquine phosphate on Babesia gibsoni in vitro and Babesia rodhaini in vivo

Parasites & Vectors, 2022
Background Drug resistance and toxic side effects are major challenges in the treatment of babesiosis. As such, new drugs are needed to combat the emergence of drug resistance in Babesia parasites and to develop alternative treatment strategies.
Shengwei Ji, Mingming Liu, Eloiza May Galon, Mohamed Abdo Rizk, Bumduuren Tuvshintulga, Jixu Li, Iqra Zafar, Yae Hasegawa, Aiko Iguchi, Naoaki Yokoyama, Xuenan Xuan   +10 more
doaj   +1 more source

Vitellogenin-2 Accumulation in the Fat Body and Hemolymph of Babesia-Infected Haemaphysalis longicornis Ticks

Frontiers in Cellular and Infection Microbiology, 2022
The protozoan parasite Babesia spp. invades into tick oocytes and remains in the offspring. The transovarial transmission phenomenon of Babesia in ticks has been demonstrated experimentally, but the molecular mechanisms remain unclear.
Maki Kuniyori, Nariko Sato, Naoaki Yokoyama, Shin-ichiro Kawazu, Xuenan Xuan, Hiroshi Suzuki, Kozo Fujisaki, Kozo Fujisaki, Rika Umemiya-Shirafuji   +8 more
doaj   +1 more source

Development of a stable transgenic Theileria equi parasite expressing an enhanced green fluorescent protein/blasticidin S deaminase

Scientific Reports, 2021
Theileria equi, an intraerythrocytic protozoan parasite, causes equine piroplasmosis, a disease which negatively impacts the global horse industry. Genetic manipulation is one of the research tools under development as a control method for protozoan ...
Bumduuren Tuvshintulga, Arifin Budiman Nugraha, Tomoka Mizutani, Mingming Liu, Takahiro Ishizaki, Thillaiampalam Sivakumar, Xuenan Xuan, Naoaki Yokoyama, Ikuo Igarashi   +8 more
doaj   +1 more source

Subolesin vaccination inhibits blood feeding and reproduction of Haemaphysalis longicornis in rabbits

Parasites & Vectors, 2020
Background Ticks can transmit numerous tick-borne pathogens and cause a huge economic loss to the livestock industry. Tick vaccines can contribute to the prevention of tick-borne diseases by inhibiting tick infestation or reproduction.
Seung-Hun Lee, Jixu Li, Paul Franck Adjou Moumouni, Kiyoshi Okado, Weiqing Zheng, Mingming Liu, Shengwei Ji, Soochong Kim, Rika Umemiya-Shirafuji, Xuenan Xuan   +9 more
doaj   +1 more source

Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo

Parasites & Vectors, 2020
Background Babesiosis represents a veterinary and medical threat, with a need for novel drugs. Artemisinin-based combination therapies (ACT) have been successfully implemented for malaria, a human disease caused by related parasites, Plasmodium spp.
Leonardo J. M. Carvalho, Bunduurem Tuvshintulga, Arifin B. Nugraha, Thillaiampalam Sivakumar, Naoaki Yokoyama   +4 more
doaj   +1 more source

Discovering the Potent Inhibitors Against Babesia bovis in vitro and Babesia microti in vivo by Repurposing the Natural Product Compounds

Frontiers in Veterinary Science, 2021
In the present study, we screened 502 natural product compounds against the in vitro growth of Babesia (B.) bovis. Then, the novel and potent identified compounds were further evaluated for their in vitro efficacies using viability and cytotoxicity ...
Yongchang Li, Yongchang Li, Mohamed Abdo Rizk, Mohamed Abdo Rizk, Eloiza May Galon, Mingming Liu, Mingming Liu, Jixu Li, Jixu Li, Aaron Edmond Ringo, Shengwei Ji, Iqra Zafar, Maria Agnes Tumwebaze, Byamukama Benedicto, Naoaki Yokoyama, Ikuo Igarashi, Bayin Chahan, Xuenan Xuan   +17 more
doaj   +1 more source

Molecular Reports of Ruminant Babesia in Southeast Asia

Pathogens, 2022
The protozoon Babesia is a blood parasite transmitted by hard ticks and commonly parasitizes ruminants such as cattle, buffaloes, goats, and sheep. Babesiosis, the disease caused by Babesia infection, has been considered a potential threat to ruminant ...
Eloiza May Galon, Iqra Zafar, Shengwei Ji, Hang Li, Zhuowei Ma, Xuenan Xuan   +5 more
doaj   +1 more source