Results 201 to 210 of about 1,052,313 (231)
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Telomerase ribonucleoprotein and genome integrity—An emerging connection in protozoan parasites
WIREs RNA, 2021Telomerase has an established role in telomere maintenance in eukaryotes. However, recent studies have begun to implicate telomerase in cellular roles beyond telomere maintenance.
Justin A. Davis, K. Chakrabarti
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Methods in molecular biology, 2021
Due to highly repetitive genome sequences, short-read-based Trypanosoma cruzi genomes are extremely fragmented. Contiguous trypanosomatid genomes assemblies have resulted in the advent of third-generation sequencing technologies. Long reads span several to hundreds of kbps allowing to correct assemblies of repeated and low complexity DNA regions ...
F. Díaz-Viraqué +3 more
semanticscholar +3 more sources
Due to highly repetitive genome sequences, short-read-based Trypanosoma cruzi genomes are extremely fragmented. Contiguous trypanosomatid genomes assemblies have resulted in the advent of third-generation sequencing technologies. Long reads span several to hundreds of kbps allowing to correct assemblies of repeated and low complexity DNA regions ...
F. Díaz-Viraqué +3 more
semanticscholar +3 more sources
Status of protozoan genome analysis: trypanosomatids
Parasitology, 1999 The three trypanosomatid genome projects have employed common strategies which include: analysis of pulsed-field gel electrophoretic chromosomal karyotypes; physical mapping using big DNA (cosmid, pacmid P1, bacterial artificial chromosome, yeast artificial chromosome) libraries; partial cDNA sequence analysis to develop sets of expressed sequence ...
J. Blackwell, S. Melville
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Protozoan genomes: gene identification and annotation
International Journal for Parasitology, 2005The draft sequence of several complete protozoan genomes is now available and genome projects are ongoing for a number of other species. Different strategies are being implemented to identify and annotate protein coding and RNA genes in these genomes, as well as study their genomic architecture.
E A, Worthey, P J, Myler
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5 - Genome Mapping of Protozoan Parasites by Linking Clones
, 1996S. Morzaria
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[2] Techniques associated with protozoan parasite genome analysis
, 1995J. Ajioka +5 more
semanticscholar +2 more sources
Nature Reviews Microbiology, 2005
The recent completion of five new protozoan parasite genomes should lead to an improved understanding of their biology and, through comparative genomics, shed light on protozoan genome diversity and evolution.
Christiane Hertz-Fowler +2 more
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The recent completion of five new protozoan parasite genomes should lead to an improved understanding of their biology and, through comparative genomics, shed light on protozoan genome diversity and evolution.
Christiane Hertz-Fowler +2 more
openaire +1 more source
The emerging paradigm of calcium homeostasis as a new therapeutic target for protozoan parasites
Medicinal research reviews (Print), 2021Calcium channels (CCs), a group of ubiquitously expressed membrane proteins, are involved in many pathophysiological processes of protozoan parasites. Our understanding of CCs in cell signaling, organelle function, cellular homeostasis, and cell cycle ...
Yash Gupta +14 more
semanticscholar +1 more source