Results 41 to 50 of about 25,444 (143)

Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi

Frontiers in Cellular and Infection Microbiology, 2021
Trypanosoma cruzi, a zoonotic kinetoplastid protozoan parasite, is the causative agent of American trypanosomiasis (Chagas disease). Having a very plastic, repetitive and complex genome, the parasite displays a highly diverse repertoire of surface ...
Carlos Talavera-López, Carlos Talavera-López, Louisa A. Messenger, Michael D. Lewis, Matthew Yeo, João Luís Reis-Cunha, Gabriel Machado Matos, Daniella C. Bartholomeu, José E. Calzada, Azael Saldaña, Juan David Ramírez, Felipe Guhl, Sofía Ocaña-Mayorga, Jaime A. Costales, Rodion Gorchakov, Kathryn Jones, Melissa S. Nolan, Santuza M. R. Teixeira, Hernán José Carrasco, Maria Elena Bottazzi, Peter J. Hotez, Kristy O. Murray, Mario J. Grijalva, Mario J. Grijalva, Barbara Burleigh, Edmundo C. Grisard, Michael A. Miles, Björn Andersson   +27 more
doaj   +1 more source

Diversity of the Microbiomes in the Larval and Adult Stages of the European Cherry Fruit Fly (Rhagoletis cerasi) and Identification of Potential Biocontrol Candidate Taxa

Entomologia Experimentalis et Applicata, EarlyView.
First comprehensive characterization of the R. cerasi microbiome is reported. Stage‐specific variations in microbial composition are documented. Multiple bacterial entomopathogen taxa are identified as potential biocontrol candidates for R. cerasi.
Mahdi N. Al‐Shammaa, Saber Delpasand Khabbazi, Remziye Nalcacioglu, Ismail Demir, Durdane Yanar, Zihni Demirbag   +5 more
wiley   +1 more source

Experimental evolution of Legionella pneumophila in mouse macrophages leads to strains with altered determinants of environmental survival. [PDF]

PLoS Pathogens, 2012
The Gram-negative bacterium, Legionella pneumophila, is a protozoan parasite and accidental intracellular pathogen of humans. We propose a model in which cycling through multiple protozoan hosts in the environment holds L.
Alexander W Ensminger, Yosuf Yassin, Alexander Miron, Ralph R Isberg   +3 more
doaj   +1 more source

Hsp70 diversification and repurposing across the tree of life: Lessons from the evolutionary and mechanistic trajectory of the Hsp70–Hsp110 chaperone system

The FEBS Journal, EarlyView.
Evolutionary and mechanistic divergence in the Hsp70–Hsp110 chaperone system. Prokaryotic Hsp70s probably diversified into multiple orthologues that cooperated with co‐chaperones such as JDPs and NEF, forming increasingly complex proteostasis networks.
Pierre Goloubinoff, Paolo De Los Rios, Mathieu E. Rebeaud   +2 more
wiley   +1 more source

New methods for the diagnosis of Babesia bigemina infection

Memorias do Instituto Oswaldo Cruz, 1992
Accurate diagnosis of Babesia bigemina infection, an economically important tick-transmitted protozoan parasite of cattle, is essential in the management of disease control and in epidemiological studies.
S. Morzaria, J. Katende, A. Kairo, V. Nene, A. Musoke   +4 more
doaj   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Development of a stable transgenic Theileria equi parasite expressing an enhanced green fluorescent protein/blasticidin S deaminase

Scientific Reports, 2021
Theileria equi, an intraerythrocytic protozoan parasite, causes equine piroplasmosis, a disease which negatively impacts the global horse industry. Genetic manipulation is one of the research tools under development as a control method for protozoan ...
Bumduuren Tuvshintulga, Arifin Budiman Nugraha, Tomoka Mizutani, Mingming Liu, Takahiro Ishizaki, Thillaiampalam Sivakumar, Xuenan Xuan, Naoaki Yokoyama, Ikuo Igarashi   +8 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Turnip mosaic virus utilizes the lipid droplet biogenesis machinery to facilitate its propagation in plants

New Phytologist, EarlyView.
Potyvirus turnip mosaic virus induces neutral lipid accumulation and lipid droplet biogenesis in infected leaves for its own benefit. Summary Lipid droplets (LDs), which are dedicated to storing neutral lipids (NLs), are dynamic organelles involved in numerous other functions, including membrane remodeling during abiotic stress.
Léna Jambou, Nathalie Arvy, Marguerite Batsale, Luc Sofer, Sara Shakir, Marielle Cochet, Vincent Simon, Charlotte Quinteau, Thomas Scotti, Nathan M. Doner, Satinder K. Gidda, Robert T. Mullen, Sabine D'Andréa, Jean‐Luc Gallois, Denis Coulon, Claire Bréhélin, Sylvie German‐Retana   +16 more
wiley   +1 more source

Improved orthologous databases to ease protozoan targets inference

Parasites & Vectors, 2015
Background Homology inference helps on identifying similarities, as well as differences among organisms, which provides a better insight on how closely related one might be to another.
Nelson Kotowski, Rodrigo Jardim, Alberto M. R. Dávila   +2 more
doaj   +1 more source