Results 221 to 230 of about 2,630,320 (343)

Near-complete genome sequences of human enterovirus A71 genotype A (BrCr-like) isolates from hand, foot, and mouth disease patients in India. [PDF]

Microbiol Resour Announc
Jagtap K, Sawant PM, Mathapati B, Roy S, Sharma V, Gogoi P, Panickan S, Lavania M.   +7 more
europepmc   +1 more source

Field-deployable viral diagnostics using CRISPR-Cas13

Science, 2018
C. Myhrvold, C. A. Freije, J. Gootenberg, O. Abudayyeh, Hayden C. Metsky, Ann F Durbin, M. Kellner, A. L. Tan, Lauren M. Paul, L. Parham, Kimberly García, K. Barnes, B. Chak, A. Mondini, M. Nogueira, S. Isern, S. Michael, I. Lorenzana, N. Yozwiak, B. MacInnis, I. Bosch, L. Gehrke, Feng Zhang, Pardis C Sabeti   +23 more
semanticscholar   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Coding-complete genome sequence of a lumpy skin disease virus (LSDV) isolate from Rajshahi, Bangladesh. [PDF]

Microbiol Resour Announc
Hossain MM, Cho H-S, Al Sium SM, Begum R, Uddin MB.   +4 more
europepmc   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Global genomic diversity of temperate P2-like viruses. [PDF]

Commun Biol
Liu Y, Liu R, Zheng K, Wang Z, Shao H, McMinn A, Wang M, Liang Y.   +7 more
europepmc   +1 more source

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity.

Cell Host and Microbe, 2018
R. Arts, S. Moorlag, B. Novaković, Yang Li, Shuang-Yin Wang, M. Oosting, Vinod Kumar, R. Xavier, C. Wijmenga, L. Joosten, C. Reusken, C. Benn, P. Aaby, M. Koopmans, H. Stunnenberg, R. van Crevel, M. Netea   +16 more
semanticscholar   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

Viral vector-based imaging uncovers infection-induced re-localization of pepino mosaic virus proteins. [PDF]

J Virol
Zhang J, Li Z, He H, Zhou X, Li F.
europepmc   +1 more source

ViPTree: the viral proteomic tree server

Bioinform., 2017
Y. Nishimura, Takashi Yoshida, M. Kuronishi, Hideya Uehara, H. Ogata, S. Goto   +5 more
semanticscholar   +1 more source