Results 161 to 170 of about 42,684,660 (287)

Genetic control of Wheat Flour End-Use Quality and Rheology via Genome-Wide Association Studies

Juan Menor de Gaspar, Julio Isidro y Sanchez, Richard Cuthbert, Brad Meyer   +3 more
openalex   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Genome-wide association studies and genomic prediction for key ornamental traits in tetraploid pot carnation

Hugo H. Tavera, Dominik Losert, Maike Boxriker, Robert Boehm, Lydia Kienbaum, Sonali Dutta, Carola Zenke‐Philippi   +6 more
openalex   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Genome-wide association study identifies candidate genes for stripe rust resistance in wheat across multiple environments

Ziyang Luo, Feifei Zhang, Mikereayi Ababaikere, Wanlong He, Wenjuan Jiao, 耿洪伟, Yukun Cheng   +6 more
openalex   +1 more source

Genome-wide association study of yield and yield-related traits in pepper (Capsicum annuum L.) [PDF]

Xiaocui Chen, Xiaowei Zhang, Shichao Sun, Hong Yang, Cheng Qin, Dan Zhou, Di Peng, Qingqing Li, 苟晓松, Ao Wang   +9 more
openalex   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Multi-Locus Genome-Wide Association Study Identifies Stable Quantitative Trait Nucleotides and Candidate Genes for Seed Protein Content in an Early-Maturing Soybean Recombinant Inbred Line Population

Quanzhong Dong, Fulin Shan, Bo Hu, Mingming Zhang, Hong Xue, Weiwei Li, Song Huan, Ming Li, Xue Qu, Wen-Xia Li, Hailong Ning   +10 more
openalex   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source