Results 201 to 210 of about 851,678 (251)

Identification of resistance sources and genomic regions regulating spot blotch resistance in Asian bread wheat (Triticum aestivum L.) via genome-wide association study. [PDF]

Plant Genome
Aggarwal N, He X, Rathore M, Jan F, Gupta V, Mir RR, Singh PK.   +6 more
europepmc   +1 more source

Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites

Advanced Functional Materials, EarlyView.
A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu, Yuqi Zhang, Alysse DeFoe, Georgios Kotsaris, Brendan Stoeckl, Matthew D. Davidson, Jason A. Burdick, Robert L. Mauck   +7 more
wiley   +1 more source

Genome-wide association study of adolescent-onset depression

Grimes PZ, Mitchell BL, Thompson KN, Deng Q, Shen X, Wolfe JC, Thomas JT, Wootton RE, Adkins DE, Arirangan S, Assary E, Chatzinakos C, Dennison CA, Gangaraju SH, Jangmo A, Jeong Y, Kurvits S, Li QS, Motazedi E, Naamanka J, Nguyen T, Nolte IM, Ota VK, Pasman JA, Shahisavandi M, Shakeshaft A, Shorter JR, Slaney C, Tesli M, Wang CA, Zubizarreta-Arruti U, PGC MDD Working Group, GLAD+, NIHR BioResource, Alemany S, Andreassen OA, Ask H, Belangero SI, Bosch R, Breen G, Bressan RA, Buil A, Byrne EM, Casas M, Copeland WE, Eley TC, Hannigan LJ, Hartman CA, Havdahl A, Hickie IB, Khandaker GM, Lehto K, Maes H, Martin NG, Neumann A, Oldehinkel AJ, Pan PM, Pan H, Pennell CE, Peterson RE, Rodriguez A, Salum GA, Vrijkotte TG, Wedow R, Whitehouse AJ, Thapar A, Larsson H, Middeldorp CM, McIntosh A, Adams MJ, Lu Y, Whalley HC, Kwong AS.   +72 more
europepmc   +1 more source

Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program. [PDF]

Diabetes
Raghavan S, Litkowski E, Jensen A, Charest B, Wang Z, Hui Q, Chen HC, Rhee MK, Leong A, Meigs JB, Lange L, Lange E, Reaven P, Hung A, Zhou J, Sun YV, Phillips LS, Million Veteran Program*.   +17 more
europepmc   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Pod Dehiscence in Soybean: Genome Wide Association Study and Genomic Prediction. [PDF]

Plants (Basel)
Mazkirat S, Bulatova K, Didorenko S, Bastaubayeva S, Babissekova D, Khalbayeva S, Tukenov A, Yespembetova A, Saparbayeva N, Shavrukov Y.   +9 more
europepmc   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Genome-wide association study reveals the genetic basis of meat quality traits in Sichuan Shelduck. [PDF]

Poult Sci
Yang Z, Xi Y, Qi J, Bai L, Zhang J, Lv J, Li B, Li L, Liu H.   +8 more
europepmc   +1 more source