Results 241 to 250 of about 3,091,688 (344)

Genome-wide association study and KASP marker development for flour color in winter wheat. [PDF]

Sci Rep
Tian Y, Liu P, Zhang X, Liu Y, Kong D, Nie Y, Xu H, Han X, Sang W, Li W.   +9 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Identification of a novel Parkinson’s disease locus via stratified genome-wide association study [PDF]

, 2014
Erin M. Hill‐Burns, William T. Wissemann, Taye H. Hamza, Stewart A. Factor, Cyrus P. Zabetian, Haydeh Payami   +5 more
openalex   +1 more source

Genome-Wide Association Study of Immune Indices in Yaks. [PDF]

Animals (Basel)
Yu D, Ma X, Huang C, Wang T, Zhang M, Feng F, Wu X, La Y, Guo X, Yan P, Zhang D, Liang C.   +11 more
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Genome-wide association study of chlamydia reinfection in African American women. [PDF]

Front Immunol
Tiwari HK, Patki A, Srinivasasainagendra V, Vejandla SC, Sadeesh A, Gupta K, Appah M, Geisler WM.   +7 more
europepmc   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Genome-wide association study of pulpal and apical diseases. [PDF]

Nat Commun
Salminen A, Hyvärinen K, Ritari J, Leppilahti JM, Palotie U, Vuollo V, Kambur O, FinnGen, Estonian Biobank Research Team, Reis K, Reigo A, Palta P, Perola M, Sinisalo J, Havulinna AS, Mäntylä P, Gürsoy UK, Suominen AL, Rice DP, Anttonen V, Nieminen P, Pussinen PJ.   +21 more
europepmc   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population [PDF]

, 2019
Ikuo Otsuka, Masato Akiyama, Osamu Shirakawa, Kenji Okazaki, Yukihide Momozawa, Yoichiro Kamatani, Takeshi Izumi, Shusuke Numata, Motonori Takahashi, Shuken Boku, Ichiro Sora, Ken Yamamoto, Yasuhiro Ueno, Tatsushi Toda, Michiaki Kubo, Akitoyo Hishimoto   +15 more
openalex   +1 more source