Results 261 to 270 of about 42,684,660 (287)

Genetic Geometry: A Unified View of Genome-Wide Association Studies and LD Score Regression

Kazuharu Misawa
openalex   +1 more source

Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez, Amy Tam, Siofra Carty, Monica Ferrer Socorro, Kathryn Yang, Darius Ebrahimi‐Fakhari   +5 more
wiley   +1 more source

Genome-wide association study and KASP development for growth and leaf traits in Populus deltoides. [PDF]

BMC Genomics
Yan J, Liu C, Zhang Z, Long K, Shen Y, Shi S.   +5 more
europepmc   +1 more source

The Etiologic Role of Trimethylamine N-Oxide in Cardiometabolic Diseases in East Asians: A Genome-Wide Association and Mendelian Randomization Study

Chenxi Li, Shan Luo, Baoting He, Hugh Simon Lam, Linda G. Snetselaar, Cherry Y. Leung, Gabriel Matthew Leung, Catherine Mary Schooling, Shiu Lun Au Yeung   +8 more
openalex   +1 more source

PCGF1 Promotes the Tumorigenesis of Malignancies Through Upregulating CCDC34 in Glioma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Polycomb group factor 1 (PCGF1) and coiled‐coil domain‐containing protein 34 (CCDC34) have been implicated in tumorigenesis in multiple malignancies. However, their biological functions and prognostic significance in glioma remain poorly defined.
Yuanbing Chen, Jianbing Xiong, Ziran Ou, Tianhao Zhao, Hui Li, Jun Huang, Zhi Tian, Wuyang Cao   +7 more
wiley   +1 more source

A genome-wide association study to identify the genetic loci underlying carbapenem resistance in Acinetobacter baumannii. [PDF]

BMC Genomics
Sekhon G, Singh B.
europepmc   +1 more source

Multi-locus genome-wide association study reveals the genetic architecture of kernel fat content in maize

Jun Zong, Xiaolong Ju, Na Liu, Dong Ding, Dong Ding, Jihua Tang, Xuehai Zhang   +6 more
openalex   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Genome-wide association study of cocaine self-administration behavior in Heterogeneous Stock rats. [PDF]

Nat Commun
Lara MK, Carrette LLG, Sanches TM, Polesskaya O, Avelar A, Beeson A, Beldjoud H, Boomhower B, Brennan M, Chen D, Cheng R, China L, Chitre AS, Conlisk DE, Fannon M, Johnson BB, Keung E, Kimbrough A, Kononoff J, Martinez AR, Maturin L, Nguyen KM, Morgan A, Mosquera J, Othman D, Plasil SL, Ramborger J, Schweitzer P, Sedighim S, Seshie O, Shankar K, Sichel B, Simpson S, Smith LC, Sneddon EA, Tieu L, Velarde N, Zahedi S, Woods LCS, Kallupi M, de Guglielmo G, Palmer AA, George O.   +42 more
europepmc   +1 more source