Results 271 to 280 of about 3,091,688 (344)

Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population

, 2009
Masakazu Nakano, Yoko Ikeda, Takazumi Taniguchi, Tomohito Yagi, Masahiro Fuwa, Natsue Omi, Yuichi Tokuda, Masami Tanaka, Kengo Yoshii, Masaaki Kageyama, Shigeta Naruse, Akira Matsuda, Kazuhiko Mori, Shigeru Kinoshita, Kei Tashiro   +14 more
openalex   +2 more sources

Loci and natural alleles for leaf length and width revealed by a genome wide association study in adzuki bean. [PDF]

BMC Plant Biol
Wu X, Wen Y, Wu K, Li R, Li X, Zhang X, Chu L, Li Y, Yang K, Wan P, Yu J, Zhao B.   +11 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Genome-wide association study of long COVID. [PDF]

Nat Genet
Lammi V, Nakanishi T, Jones SE, Andrews SJ, Karjalainen J, Cortés B, O'Brien HE, Ochoa-Guzman A, Fulton-Howard BE, Broberg M, Haapaniemi HH, Kanai M, Pirinen M, Schmidt A, Mitchell RE, Mousas A, Mangino M, Huerta-Chagoya A, Sinnott-Armstrong N, Cirulli ET, Vaudel M, Kwong ASF, Maiti AK, Marttila MM, Posner DC, Rodriguez AA, Batini C, Minnai F, Dearman AR, Warmerdam CAR, Sequeros CB, Winkler TW, Jordan DM, Rešcenko R, Miano L, Lane JM, Chung RK, Guillen-Guio B, Leavy OC, Carvajal-Silva L, Aguilar-Valdés K, Frangione E, Guare L, Vergasova E, Marouli E, Striano P, Zainulabid UA, Kumar A, Ahmad HF, Edahiro R, Azekawa S, Long COVID Host Genetics Initiative, FinnGen, VA Million Veteran Program, MexGen-COVID Initiative, DBDS Genomic Consortium, GEN-COVID Multicenter Study, PHOSP-COVID Collaborative Group, GENCOV Study, Estonian Biobank Research Team, Luoh SW, Erikstrup C, Pedersen OBV, Lerner-Ellis J, Colombo A, Grzymski JJ, Ishii M, Okada Y, Beckmann ND, Kumari M, Wagner R, Heid IM, John C, Short PJ, Magnus P, Ansone L, Valenti LVC, Lee SA, Wain LV, Verdugo RA, Banasik K, Geller F, Franke LH, Rakitko A, Duncan EL, Renieri A, Tsilidis KK, de Cid R, Niavarani A, Abner E, Tusié-Luna T, Verma SS, Smith GD, Smith GD, Timpson NJ, Madduri RK, Cho K, Daly MJ, Ganna A, Schulte EC, Richards JB, Ludwig KU, Marks-Hultström M, Zeberg H, Ollila HM.   +104 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

A Genome‐Wide Association Study of Apple Quality and Scab Resistance

, 2018
Kendra A. McClure, Kyle M. Gardner, Gavin M. Douglas, Jun Song, Charles F. Forney, John M. DeLong, Lihua Fan, Lina Du, P.M.A. Toivonen, Daryl J. Somers, Istvan Rajcan, Sean Myles   +11 more
openalex   +1 more source

Genome-wide association study reveals candidate loci on ECA1 and ECA9 for withers height in Friesian horses. [PDF]

Anim Genet
Steensma MJ, Doekes HP, Derks MFL, Ducro BJ.   +3 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Genome-Wide Association Study of Abdominal and Intramuscular Fat Deposition Traits in Huainan Yellow-Feathered Chickens. [PDF]

Animals (Basel)
Dai Z, Li Y, Liu J, Chen R, Zhu H, Lei M.   +5 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source