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Genome-wide association study of adolescent-onset depression

Grimes PZ, Mitchell BL, Thompson KN, Deng Q, Shen X, Wolfe JC, Thomas JT, Wootton RE, Adkins DE, Arirangan S, Assary E, Chatzinakos C, Dennison CA, Gangaraju SH, Jangmo A, Jeong Y, Kurvits S, Li QS, Motazedi E, Naamanka J, Nguyen T, Nolte IM, Ota VK, Pasman JA, Shahisavandi M, Shakeshaft A, Shorter JR, Slaney C, Tesli M, Wang CA, Zubizarreta-Arruti U, PGC MDD Working Group, GLAD+, NIHR BioResource, Alemany S, Andreassen OA, Ask H, Belangero SI, Bosch R, Breen G, Bressan RA, Buil A, Byrne EM, Casas M, Copeland WE, Eley TC, Hannigan LJ, Hartman CA, Havdahl A, Hickie IB, Khandaker GM, Lehto K, Maes H, Martin NG, Neumann A, Oldehinkel AJ, Pan PM, Pan H, Pennell CE, Peterson RE, Rodriguez A, Salum GA, Vrijkotte TG, Wedow R, Whitehouse AJ, Thapar A, Larsson H, Middeldorp CM, McIntosh A, Adams MJ, Lu Y, Whalley HC, Kwong AS.   +72 more
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Genome‐wide androgenetic mosaicism

Clinical Genetics, 2013
Individuals with mosaic paternal uniparental disomy (UPD) of apparently all chromosomes have recently been described. They show a 46,XX karyotype, but with a mixture of normal biparental cells and cells entirely of paternal isodisomic origin. We describe an infant who primarily showed signs of Beckwith–Wiedemann syndrome (BWS), but also had other ...
J P, Johnson, J, Waterson, C, Schwanke, J, Schoof   +3 more
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Inbreeding in genome‐wide selection

Journal of Animal Breeding and Genetics, 2007
SummaryTraditional selection methods, such as sib and best linear unbiased prediction (BLUP) selection, which increased genetic gain by increasing accuracy of evaluation have also led to an increased rate of inbreeding per generation (ΔFG). This is not necessarily the case with genome‐wide selection, which also increases genetic gain by increasing ...
Daetwyler, H.D., Villanueva, B., Bijma, P., Woolliams, J.A.   +3 more
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Genome-Wide Association Studies

2012
A host of data on genetic variation from the Human Genome and International HapMap projects, and advances in high-throughput genotyping technologies, have made genome-wide association (GWA) studies technically feasible. GWA studies help in the discovery and quantification of the genetic components of disease risks, many of which have not been unveiled ...
Tun-Hsiang, Yang, Mark, Kon, Charles, DeLisi   +2 more
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