Results 241 to 250 of about 3,210,341 (315)

Deep Learning Enables Genome-Wide Association Studies of Microvascular Features

Elwakil A, Strebel S, Charbonnier M, Quiros JV, Liefers B, Belatchane L, Foa N, Bergmann S, Klaver C, Bergin C, Schlingemann R, VascX Research Consortium, Tomasoni M, Meloni I.   +13 more
europepmc   +1 more source

Genome-wide association study of atopic and autoimmune comorbidities in alopecia areata. [PDF]

Front Immunol
Herrera-Rivero M, Gossmann Y, Awasthi S, Cesarato N, Ripke S, Blaumeiser B, Blume-Peytavi U, Lutz G, Redler S, Nöthen MM, Betz RC, Basmanav FB.   +11 more
europepmc   +1 more source

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos, Morgan C. Devore, Christina Lam, Courtney Park, Sanjay Bidichandani, David R. Lynch   +5 more
wiley   +1 more source

Clade distillation for genome-wide association studies. [PDF]

Genetics
Christ R, Wang X, Aslett LJM, Steinsaltz D, Hall I.   +4 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Genome-wide identification and gene expression analysis of AhNHXs in peanut. [PDF]

BMC Plant Biol
Zhou Y, Xie Q, Liang Z, Chen T, Feng E, Lin Q, Hu H, Xue Y, Jiang X, Liu Y.   +9 more
europepmc   +1 more source

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

Genome-Wide Linkage Mapping for Mixograph Properties in Common Wheat. [PDF]

Plants (Basel)
Zhang Q, Liu F, Cao W, Li Y, Lv Y, Zhou H, Du X, Wan Y, Ma C.   +8 more
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Late blight resistance of Julius Kühn Institute pre-breeding potato clones: a genome-wide association study. [PDF]

BMC Plant Biol
Blossei J, Gäbelein R, Hammann T, Kirchgesser J, Uptmoor R.   +4 more
europepmc   +1 more source