Results 231 to 240 of about 1,107,991 (320)

Genome-wide association studies unravel genomic regions and candidate genes associated with Aspergillus flavus resistance in peanut kernels. [PDF]

Theor Appl Genet
Cui M, Guo J, Qi F, Sun Z, Chen L, Wu Z, Xu X, Wang X, Zhang M, Huang B, Dong W, Zhang X, Han S.   +12 more
europepmc   +1 more source

Using mathematical models of biological processes in genome-wide association studies of psychiatric disorders [PDF]

, 2017
Cochran, Amy
core   +1 more source

A versatile gene-based test for genome-wide association studies.

American Journal of Human Genetics, 2010
J. Liu, A. McRae, D. Nyholt, S. Medland, N. Wray, K. Brown, N. Hayward, G. Montgomery, P. Visscher, N. Martin, S. Macgregor   +10 more
semanticscholar   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Deep Learning Enables Genome-Wide Association Studies of Microvascular Features

Elwakil A, Strebel S, Charbonnier M, Quiros JV, Liefers B, Belatchane L, Foa N, Bergmann S, Klaver C, Bergin C, Schlingemann R, VascX Research Consortium, Tomasoni M, Meloni I.   +13 more
europepmc   +1 more source

A Categorical ANCOVA Approach to Severity Endophenotype-Specific Genome-Wide Association Studies in Childhood Asthma. [PDF]

J Pers Med
Piparia S, Hadikhani P, Ziniti J, Hecker J, Kho AT, Sharma R, Celedón JC, McGeachie MJ, Weiss ST, Tantisira KG.   +9 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Immune cell signatures and preeclampsia: Unveiling causal links through genome-wide association studies. [PDF]

Medicine (Baltimore)
Zhang H, Zu Y, Zu Y, Xiu X, Yi H, Xu X, Yan J.   +6 more
europepmc   +1 more source

Estimating missing heritability for disease from genome-wide association studies.

American Journal of Human Genetics, 2011
S. Lee, N. Wray, M. Goddard, P. Visscher
semanticscholar   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source