Results 211 to 220 of about 450,356 (259)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Insights from farming Macrocystis pyrifera offshore: phenotypic analysis, genome-wide association studies, genomic selection. [PDF]

Heredity (Edinb)
Kovalev M, Montecinos Arismendi G, Yorke C, Wade RM, Molano G, Miller R, Reed D, Alberto F, Nuzhdin S.   +8 more
europepmc   +1 more source

Remote Activation of Wnt Signaling and Cell Proliferation by E‐Cadherin Magnetomechanical Stimulation

Advanced Functional Materials, EarlyView.
A pioneering magnetogenetic toolkit enables non‐invasive, precise spatiotemporal modulation of intracellular Wnt/β‐catenin signaling. Functionalized magnetic nanoparticles (MNPs@E/EC15) target cellular E‐cadherins to generate localized magnetomechanical forces under low‐intensity magnetic fields.
Christian Castro‐Hinojosa, Pablo Martínez‐Vicente, Lucía G. Recaredo, Susel Del Sol‐Fernández, Pilar Gomollón‐Zueco, Yilian Fernández‐Afonso, Raluca M. Fratila, María Moros   +7 more
wiley   +1 more source

Genome-wide association studies and QTL mapping for traits deviating from normal distribution. [PDF]

Natl Sci Rev
Tang Y, Li M, Liu D, Jiang L, Li Q, Wang J, Yu H, Xu S.   +7 more
europepmc   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Genome-Wide Association Studies Reveal Key Candidate Genes for Egg Weight and Quality Components in an F₂ Japanese Quail Resource Population. [PDF]

Vet Sci
Volkova NA, Romanov MN, Larionova PV, German NY, Volkova LA, Sermyagin AA, Shakhin AV, Griffin DK, Sölkner J, Zinovieva NA.   +9 more
europepmc   +1 more source

Genotype-by-sequencing-enabled genome-wide association studies reveal genetic architecture of biomass and nitrogen modulation in tepary bean (Phaseolus acutifolius). [PDF]

G3 (Bethesda)
Reddy Alla SK, Joshi V.
europepmc   +1 more source

Genome-Wide Association Studies of Milk Composition Traits in Holstein Cattle Raised in Tropical and Subtropical Conditions. [PDF]

Animals (Basel)
Silva EFP, Gaia RC, Mulim HA, Pinto LFB, Iung LHS, Brito LF, Pedrosa VB.   +6 more
europepmc   +1 more source

Translating genome-wide association studies at multiple scales: Drug target prioritization, cellular architectures, and organ imaging. [PDF]

Cell Genom
Felici B, Chen S, Yuan M, Jiang X, Ip S, Rudd JHF, Inouye M.   +6 more
europepmc   +1 more source

Exploring the genetic correlation between inflammatory bowel disease and psychiatric disorders: insights from genome-wide association studies. [PDF]

Eur Arch Psychiatry Clin Neurosci
Zhang J, Shen J, Liu L.
europepmc   +1 more source