Results 191 to 200 of about 450,356 (259)

Multi-model genome-wide association studies identify stable QTLs and candidate genes for lodging resistance in <i>indica</i> rice. [PDF]

Front Plant Sci
Luo X, Cao J, Yin D, Dong H, Wang H, Hu J, Xue L, Hu P, Liu D, Wen Y, Chen D, Wang J, Li L, Xu D, Zheng X.   +14 more
europepmc   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Genome-Wide Association Studies in Hepatocellular Carcinoma: Aetiology-Specific Susceptibility, Functional Interpretation, and Clinical Translation. [PDF]

Genes (Basel)
Zhang S, Long X.
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Genome-Wide Association Studies for 24 Hematological Traits in Production Pigs Before and After Weaning. [PDF]

Anim Genet
Sun J, Ibragimov E, Morsing MK, Rydal MP, Nielsen LN, Cai Z, Nielsen JP, Fredholm M, Karlskov-Mortensen P.   +8 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Genome-wide association studies of body weight, body conformation traits and coat color in Gamba sheep. [PDF]

Anim Biosci
Zhang Y, Zhou H, Gesang L, Zhaxi D, Pubu C, Miao H, Zhang J, Zhao Y.   +7 more
europepmc   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Deep Learning Enables Genome-Wide Association Studies of Microvascular Features

Elwakil A, Strebel S, Charbonnier M, Quiros JV, Liefers B, Belatchane L, Foa N, Bergmann S, Klaver C, Bergin C, Schlingemann R, VascX Research Consortium, Tomasoni M, Meloni I.   +13 more
europepmc   +1 more source

BaGPipe: an automated, reproducible, and flexible pipeline for bacterial genome-wide association studies. [PDF]

BMC Microbiol
Wei KC, Blane B, Toussaint J, Reuter S, Toleman MS, Torok ME, Peacock SJ, Harrison EM, Aggarwal D, Roberts-Sengier W.   +9 more
europepmc   +1 more source