Results 181 to 190 of about 1,107,991 (320)

Clade distillation for genome-wide association studies. [PDF]

Genetics
Christ R, Wang X, Aslett LJM, Steinsaltz D, Hall I.   +4 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Genome-Wide Association Studies of Myocardial Infarction: A Systematic Literature Review. [PDF]

J Cardiovasc Dev Dis
Thierry IP, Jabbari R, Engstrøm T, Tfelt-Hansen J, Glinge C.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Genome-Wide Association Studies for 24 Hematological Traits in Production Pigs Before and After Weaning. [PDF]

Anim Genet
Sun J, Ibragimov E, Morsing MK, Rydal MP, Nielsen LN, Cai Z, Nielsen JP, Fredholm M, Karlskov-Mortensen P.   +8 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Genome-wide association studies for identifying SNPs and candidate genes associated with grain quality traits in rice (Oryza sativa L.). [PDF]

Plant Genome
Darmagaru S, Rahaman AF, Jabeen F, Jukanti AK, Kasarla C, Gowdru Dhananjaya DK, Tamilarasu A, Subba Rao L, Kallakuri S, Venkatanagappa S, Sundaram RM.   +10 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Genetic architecture of plasma pTau217 and related biomarkers in Alzheimer's disease via genome-wide association studies. [PDF]

Alzheimers Dement
Kim JP, Song M, Cho M, Lee H, Jung SH, Lim S, Kim C, Jang B, Shin D, Kang H, Yim S, Jang H, Kim BH, Kim HJ, Na DL, An JY, Zetterberg H, Blennow K, Gonzalez-Ortiz F, Ashton NJ, Day TA, Seo SW, Won HH.   +22 more
europepmc   +1 more source

Genome-wide association studies identify new melanoma susceptibility loci [PDF]

, 2012
Dębniak Tadeusz
core   +1 more source