Results 171 to 180 of about 850,713 (297)

Figure 3 from Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma

Karen Alpen, Robert J. MacInnis, Claire M. Vajdic, John Lai, James G. Dowty, Eng‐Siew Koh, Elizabeth Hovey, Rosemary Harrup, Tuong L. Nguyen, Shuai Li, David Joseph, Geza Benke, Pierre‐Antoine Dugué, Melissa C. Southey, Graham G. Giles, Anna K. Nowak, Katharine J. Drummond, Daniel F. Schmidt, John L. Hopper, Miroslaw K. Kapuscinski, Enes Makalic   +20 more
openalex   +1 more source

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status [PDF]

, 2019
Paul Lyons, James E. Peters, Federico Alberici, James Liley, Richard Coulson, William J. Astle, Chiara Baldini, Francesco Bonatti, María C. Cid, Heather Elding, Giacomo Emmi, Jörg T. Epplen, Loı̈c Guillevin, David Jayne, Tao Jiang, Iva Gunnarsson, Peter Lamprecht, Stephen Leslie, Mark A. Little, Davide Martorana, Frank Moosig, Thomas Neumann, Sophie Ohlsson, Stefanie Quickert, Giuseppe A. Ramirez, Barbara Rewerska, Georg Schett, Renato Alberto Sinico, Wojciech Szczeklik, Vladimı́r Tesař, Damjan Vukcevic, Mohammed Akil, Jonathan Barratt, Neil Basu, Adam S. Butterworth, Ian N Bruce, Michael Clarkson, Niall Conlon, Bhaskar Dasgupta, Timothy Doulton, Georgina Espígol‐Frigolé, Oliver Floßmann, Tianlu Li, Jolanta Gąsior, Gina Gregorini, Giuseppe Guida, José Hernández‐Rodríguez, Zdenka Hrušková, Amy W. Hudson, Ann Knight, Peter Lanyon, Raashid Luqmani, Malgorzata Magliano, Angelo A. Manfredi, Christopher Marguerie, Federica Maritati, Chiara Marvisi, Neil McHugh, Eamonn Molloy, Allan Motyer, Chetan Mukhtyar, Leonid Padyukov, Alberto Pesci, Sergio Prieto‐González, Marc Ramentol-Sintas, Petra Reis, Dario Roccatello, Patrizia Rovere‐Querini, Carlo Salvarani, Francesca Santarsia, Roser Solans‐Laqué, Nicole Soranzo, Jo Taylor, Julie Wessels, Jochen Zwerina, Benjamin Terrier, Richard A. Watts, Augusto Vaglio, Julia U. Holle, Chris Wallace, Kenneth G. C. Smith   +80 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Genome-Wide Association Study of First-Parity Reproductive Traits in Suzi Pig. [PDF]

Genes (Basel)
Fu Y, Li W, Dai C, Liao C, Cheng J, Li H, Zhao W.   +6 more
europepmc   +1 more source

Causal relationship between multiple sclerosis and asthma and chronic obstructive pulmonary disease based on genome-wide association study data

Wenhui Cui, Ting-Ting Wu, Keqing Shi, Xin Wang, Shuyu Chen, Mengjun Cao, Aolong Xu, Yingzhi Chong, Xueli Zhang, Qiang Wang   +9 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Genome-Wide Association Study of Daughter Pregnancy Rate in Crossbred Dairy Cows. [PDF]

Int J Mol Sci
Yang R, Liang Z, Prakapenka D, Ma L, Da Y.   +4 more
europepmc   +1 more source

Genome-wide association study of lung function decline in adults with and without asthma [PDF]

, 2012
Medea Imboden, Emmanuelle Bouzigon, Ivan Curjuric, Adaikalavan Ramasamy, Ashish Kumar, Dana B. Hancock, Jemma B. Wilk, Judith M. Vonk, Gian Andri Thun, Valérie Siroux, Rachel Nadif, Florent Monier, Juan R. González, Matthias Wjst, Joachim Heinrich, Laura R. Loehr, Nora Franceschini, Kari E. North, Janine Altmüller, Gerard H. Koppelman, Stefano Guerra, Florian Kronenberg, Mark Lathrop, Miriam F. Moffatt, George O'connor, David P. Strachan, Dirkje S. Postma, Stephanie J. London, Christian Schindler, Manolis Kogevinas, F. Kauffmann, Deborah Jarvis, Florence Démenais, Nicole Probst‐Hensch   +33 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source