Results 231 to 240 of about 674,070 (352)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Genome-wide association study of REM sleep behavior disorder in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Sosero YL, Heilbron K, Fontanillas P, Norcliffe-Kaufmann L, Yu E, Rudakou U, Ruskey JA, Freeman K, Asayesh F, Brolin KA, Swanberg M, Morris HR, Wu L, Real R, Pihlstrøm L, Tan M, Gasser T, Brockmann K, Liu H, Hu MTM, Grosset DG, Lewis SJG, Kwok JB, Pastor P, Alvarez I, Skorvanek M, Lackova A, Ostrozovicova M, Rizig M, 23andMe Research Team, International Parkinson’s Disease Genomics Consortium, Krohn L, Gan-Or Z.   +32 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Genetic Basis of Egg Production in Baicheng-You Chickens: A Genome-Wide Association Study. [PDF]

Animals (Basel)
You G, Jiang T, Li H, Dong W, Zhao X, Zhang S, Hou Z, Liao H, Yin Z.   +8 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Genome-Wide Association Study Identifies Candidate Genes for Body Size Traits in Wanyue Black Pigs. [PDF]

Animals (Basel)
Ye H, Li W, Tian F, Wang Q, Ma Z, Guan J, Ding Y, Zheng X, Yin Z, Zhang X.   +9 more
europepmc   +1 more source

Genome-Wide Association Study of Abdominal and Intramuscular Fat Deposition Traits in Huainan Yellow-Feathered Chickens [PDF]

Zichun Dai, Yaxin Li, Jie Liu, Rong Chen, Huanxi Zhu, Mingming Lei   +5 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Genome-wide association study of susceptibility to acute respiratory distress syndrome. [PDF]

EBioMedicine
Guillen-Guio B, Suarez-Pajes E, Tosco-Herrera E, Hernandez-Beeftink T, Lorenzo-Salazar JM, Chang D, González-Montelongo R, Rubio-Rodríguez LA, Leavy OC, Allen RJ, Corrales A, Cruz R, Bardají-Carrillo M, Carracedo A, Tamayo E, Kerchberger VE, Ware LB, Yaspan BL, Scholz M, Scherag A, Villar J, Wain LV, Flores C.   +22 more
europepmc   +1 more source

Additional file 3 of Characterization of genome-wide association study data reveals spatiotemporal heterogeneity of mental disorders

, 2020
Yulin Dai, Timothy O’Brien, Guangsheng Pei, Zhongming Zhao, Peilin Jia   +4 more
openalex   +1 more source