Results 191 to 200 of about 4,524,973 (357)
Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller +6 morewiley +1 more sourceInitial sequencing and analysis of the human genome
Nature, 2001 E. Lander, L. Linton, B. Birren, C. Nusbaum, M. Zody, J. Baldwin, K. Devon, K. Dewar, M. Doyle, W. Fitzhugh, R. Funke, D. Gage, K. Harris, A. Heaford, J. Howland, L. Kann, J. Lehoczky, R. Levine, P. McEwan, K. McKernan, J. Meldrim, J. Mesirov, C. Miranda, W. Morris, J. Naylor, C. Raymond, M. Rosetti, R. Santos, A. Sheridan, C. Sougnez, Y. Stange-Thomann, N. Stojanovic, A. Subramanian, D. Wyman, J. Rogers, J. Sulston, R. Ainscough, S. Beck, D. Bentley, J. Burton, C. Clee, N. Carter, A. Coulson, R. Deadman, P. Deloukas, A. Dunham, I. Dunham, R. Durbin, L. French, D. Grafham, S. Gregory, T. Hubbard, S. Humphray, A. Hunt, M. Jones, C. Lloyd, A. McMurray, L. Matthews, S. Mercer, S. Milne, J. Mullikin, A. Mungall, R. Plumb, M. Ross, R. Shownkeen, S. Sims, R. Waterston, R. Wilson, L. Hillier, J. McPherson, M. Marra, E. Mardis, L. Fulton, A. Chinwalla, K. Pepin, W. Gish, S. Chissoe, M. Wendl, K. Delehaunty, T. Miner, A. Delehaunty, J. Kramer, L. Cook, R. Fulton, D. Johnson, P. Minx, S. Clifton, T. Hawkins, E. Branscomb, P. Predki, P. Richardson, S. Wenning, T. Slezak, N. Doggett, J. Cheng, A. Olsen, S. Lucas, C. Elkin, E. Uberbacher, M. Frazier, R. Gibbs, D. Muzny, S. Scherer, J. Bouck, E. Sodergren, K. Worley, C. Rives, J. H. Gorrell, M. Metzker, S. Naylor, R. Kucherlapati, D. Nelson, G. Weinstock, Y. Sakaki, A. Fujiyama, M. Hattori, T. Yada, A. Toyoda, T. Itoh, C. Kawagoe, H. Watanabe, Y. Totoki, T. Taylor, J. Weissenbach, R. Heilig, W. Saurin, F. Artiguenave, P. Brottier, T. Bruls, É. Pelletier, C. Robert, P. Wincker, D. Smith, L. Doucette-Stamm, M. Rubenfield, K. Weinstock, H. M. Lee, J. Dubois, A. Rosenthal, M. Platzer, G. Nyakatura, S. Taudien, A. Rump, H. Yang, J. Yu, J. Wang, G. Huang, J. Gu, L. Hood, L. Rowen, A. Madan, S. Qin, R. W. Davis, N. Federspiel, A. Abola, M. Proctor, R. M. Myers, J. Schmutz, M. Dickson, J. Grimwood, D. Cox, M. Olson, R. Kaul, N. Shimizu, K. Kawasaki, S. Minoshima, G. Evans, M. Athanasiou, R. Schultz, B. Roe, F. Chen, H. Pan, J. Ramser, H. Lehrach, R. Reinhardt, W. McCombie, M. de la Bastide, N. Dedhia, H. Blöcker, K. Hornischer, G. Nordsiek, R. Agarwala, L. Aravind, J. Bailey, A. Bateman, S. Batzoglou, E. Birney, P. Bork, D. Brown, C. Burge, L. Cerutti, H. Chen, D. Church, M. Clamp, R. Copley, T. Doerks, S. Eddy, E. Eichler, T. Furey, J. Galagan, J. Gilbert, C. Harmon, Y. Hayashizaki, D. Haussler, H. Hermjakob, K. Hokamp, W. Jang, L. S. Johnson, T. A. Jones, S. Kasif, A. Kaspryzk, S. Kennedy, W. Kent, P. Kitts, E. Koonin, I. Korf, D. Kulp, D. Lancet, Gwênlyn Glusman, T. Lowe, A. McLysaght, T. Mikkelsen, J. V. Moran, N. Mulder, V. J. Pollara, C. Ponting, G. Schuler, J. Schultz, G. Slater, A. Smit, E. Stupka, J. Szustakowki, D. Thierry-Mieg, J. Thierry-Mieg, L. Wagner, J. Wallis, R. Wheeler, A. Williams, Y. I. Wolf, K. H. Wolfe, S. Yang, R. Yeh, F. Collins, M. Guyer, J. Peterson, A. Felsenfeld, K. Wetterstrand, A. Patrinos, M. Morgan, P. D. de Jong, J. Catanese, K. Osoegawa, H. Shizuya, S. Choi, Y. J. Chen, Vacslav Glukhov +255 moresemanticscholar +1 more sourceFGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma +3 morewiley +1 more sourceHighly heterozygous Citrus changshan-huyou Y. B. Chang originated from ancient hybridization between mandarin and pummelo and displayed distinct tissue-specific allelic imbalance. [PDF]
Plant GenomeZeng Z, Luo Y, Hu H, Lan L, Guo B, Zhou P, Tan C, Huang X, Qi T, Chen Z, Yu Z, Wang L, Xiang T, Li C, Jia Y. +14 moreeuropepmc +1 more sourceKLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul +6 morewiley +1 more source
