Results 231 to 240 of about 3,743,554 (329)

Ein Konstruktionsalgorithmus einer Indexstruktur für Genome

, 2005
Gabriele Witterstein
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Global Comparative Genomics of <i>Stenotrophomonas</i> <i>maltophilia</i> Reveals Cryptic Species Diversity, Resistome Variation, and Population Structure. [PDF]

Life (Basel)
Thant EP, Klaysubun C, Suwannasin S, Dechathai T, Singkhamanan K, Yaikhan T, Chaichana N, Pomwised R, Wonglapsuwan M, Chusri S, Surachat K.   +10 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

On the use and misuse of pangenome and related terms. [PDF]

Nat Commun
Edwards D.
europepmc   +1 more source

Characterization of Blood Group Variants in an Omani Population by Comparison of Whole Genome Sequencing and Serology

Paige E. Haffener, Arwa Z. Al‐Riyami, Shoaib Al‐Zadjali, Mohammed Al‐Rawahi, Saif Al Hosni, Ali Al Marhoobi, Ammar Al Sheriyani, Ellen M. Leffler   +7 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

CRISPR genome editing using a combined positive and negative selection system

Ishrya Sharma, Kelly Hall, Shannon Moonah   +2 more
openalex   +1 more source

Comparative genomics and genome evolution.

Current genomics, 2012
Das, Sabyasachi, Hirano, Masayuki
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source