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Genomics and functional genomics with haloarchaea
Archives of Microbiology, 2008The first haloarchaeal genome was published in 2000 and today five genome sequences are available. Transcriptome and proteome analyses have been established for two and three haloarchaeal species, respectively, and more than 20 studies using these functional genomic approaches have been published in the last two years.
J, Soppa +5 more
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Combing the genome for genomic instability
Trends in Biotechnology, 2002Genomic instability is one of the major features of cancer cells. The clinical phenotypes associated with several human diseases have been linked to recurrent DNA rearrangements and dysfunction of DNA replication processes that involve unstable genomic regions.
Caburet, Sandrine +2 more
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The ‘Persons‘ and ‘Genomics‘ of Personal Genomics
Personalized Medicine, 2010At stake in the debate about personal genomics is what kind of person can be trusted to interpret genomes. Deciding this hinges not just on determining if consumers can interpret genomic information, but on deciding which biological and medical experts (if any) can perform these interpretive acts.
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Science, 2012
As genomic sequencing projects attempt ever more ambitious integration of genetic, molecular, and phenotypic information, a specialization of genomics has emerged, embodied in the subdiscipline of computational genomics. Models inherited from population genetics, phylogenetics, and human disease genetics merge with those from graph theory,
Zerbino, D. R., Paten, B., Haussler, D.
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As genomic sequencing projects attempt ever more ambitious integration of genetic, molecular, and phenotypic information, a specialization of genomics has emerged, embodied in the subdiscipline of computational genomics. Models inherited from population genetics, phylogenetics, and human disease genetics merge with those from graph theory,
Zerbino, D. R., Paten, B., Haussler, D.
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2011
The science of genomes: only within the past few decades have scientists progressed from the analysis of a single or a small number of genes at once to the investigation of thousands of genes, going from the study of the units of inheritance to the investigation of the whole genome of an organism.
L. Del Giacco, C. Cattaneo
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The science of genomes: only within the past few decades have scientists progressed from the analysis of a single or a small number of genes at once to the investigation of thousands of genes, going from the study of the units of inheritance to the investigation of the whole genome of an organism.
L. Del Giacco, C. Cattaneo
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2013
Genome walking is a method for determining the DNA sequence of unknown genomic regions flanking a region of known DNA sequence. The Genome walking has the potential to capture 6-7 kb of sequence in a single round. Ideal for identifying gene promoter regions where only the coding region.
Shapter, Frances M, Waters, Daniel L E
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Genome walking is a method for determining the DNA sequence of unknown genomic regions flanking a region of known DNA sequence. The Genome walking has the potential to capture 6-7 kb of sequence in a single round. Ideal for identifying gene promoter regions where only the coding region.
Shapter, Frances M, Waters, Daniel L E
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Physiological Genomics, 2004
Abstract Nutrients and other food components are amongst the most persistent, variable (both in terms of the nature and abundance of the food supply), and essential environmental exposures for all life forms. The need for organisms to balance constant nutrient ‘‘need’’ with intermittent nutrient ‘‘availability’’ has driven the evolution ...
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Abstract Nutrients and other food components are amongst the most persistent, variable (both in terms of the nature and abundance of the food supply), and essential environmental exposures for all life forms. The need for organisms to balance constant nutrient ‘‘need’’ with intermittent nutrient ‘‘availability’’ has driven the evolution ...
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2006
The chicken has long been an important model organism for developmental biology, as well as a major source of protein with billions of birds used in meat and egg production each year. Chicken genomics has been transformed in recent years, with the characterisation of large EST collections and most recently with the assembly of the chicken genome ...
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The chicken has long been an important model organism for developmental biology, as well as a major source of protein with billions of birds used in meat and egg production each year. Chicken genomics has been transformed in recent years, with the characterisation of large EST collections and most recently with the assembly of the chicken genome ...
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Science, 1997
This year's Genome Issue goes one step beyond the genome project. In its broadest sense, the issue is concerned with taking the sequence information that is the output of the project to the next level—making it useful in studies ranging from understanding the function associated with the sequence to making the transition from gene discovery to the ...
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This year's Genome Issue goes one step beyond the genome project. In its broadest sense, the issue is concerned with taking the sequence information that is the output of the project to the next level—making it useful in studies ranging from understanding the function associated with the sequence to making the transition from gene discovery to the ...
openaire +3 more sources