Results 71 to 80 of about 4,323,813 (404)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways. [PDF]
, 2008 Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation.
Cancer Genome Atlas Research Network
core +1 more source
Genome sequence and genetic linkage analysis of Shiitake mushroom _Lentinula edodes_ [PDF]
, 2012 _Lentinula edodes_ (Shiitake/Xianggu) is an important cultivated mushroom. Understanding the genomics and functional genomics of _L. edodes_ allows us to improve its cultivation and quality.
Chun Hang Au +10 more
core +2 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Genomic parasites and genome evolution [PDF]
Genome Biology, 2009 A report of the Second International Conference/Workshop on the Genomic Impact of Eukaryotic Transposable Elements, Pacific Grove, USA, 6-10 February 2009.
openaire +3 more sources
Validation of a guidelines-based digital tool to assess the need for germline cancer genetic testing
Hereditary Cancer in Clinical PracticeBackground Efficient and scalable solutions are needed to identify patients who qualify for germline cancer genetic testing. We evaluated the clinical validity of a brief, patient-administered hereditary cancer risk assessment digital tool programmed to ...
Callan D. Russell +10 more
doaj +1 more source
Frontiers in Microbiology, 2018 The genus Nitrospira represents a dominant group of nitrite-oxidizing bacteria in natural and engineered ecosystems. This genus is phylogenetically divided into six lineages, for which vast phylogenetic and functional diversity has been revealed by ...
Norisuke Ushiki +5 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Bovine tuberculosis caused by Mycobacterium bovis, is a significant global pathogen causing economic loss in livestock and zoonotic TB in man. Several vaccine approaches are in development including reverse vaccinology which uses an unbiased approach to ...
Deepa Paliwal +6 more
doaj +1 more source
Accelerating Genome Analysis via Algorithm-Architecture Co-Design [PDF]
arXiv, 2023 High-throughput sequencing (HTS) technologies have revolutionized the field of genomics, enabling rapid and cost-effective genome analysis for various applications. However, the increasing volume of genomic data generated by HTS technologies presents significant challenges for computational techniques to effectively analyze genomes.
arxiv
GDC 2: Compression of large collections of genomes [PDF]
Scientific Reports, Article no. 11565 (2015), 2015 The fall of prices of the high-throughput genome sequencing changes the landscape of modern genomics. A number of large scale projects aimed at sequencing many human genomes are in progress. Genome sequencing also becomes an important aid in the personalized medicine.
arxiv +1 more source
Genome sequence of a novel alloherpesvirus isolated from glass catfish (Kryptopterus bicirrhis) [PDF]
, 2018 The 149,343-bp genome of silurid herpesvirus 1, which was isolated in Thailand from glass catfish, was sequenced. The genome was most closely related to that of ictalurid herpesvirus 2, which infects black bullhead catfish. To our knowledge, this was the
Davison, Andrew J. +5 more
core +1 more source