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Genomic analysis

Current Opinion in Biotechnology, 2000
Advances in genomic analysis include improved technology for DNA sequencing, routine use of DNA microarray technology for the analysis of gene expression profiles at the mRNA level and improved informatic tools to organize and analyze such data. At the same time, new developments in chip-based analysis of samples and the emergence of models of gene ...
P S, Lee, K H, Lee
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Genome comparisons and analysis

Current Opinion in Structural Biology, 2003
As we enter the post-genomic era, with the accelerating availability of complete genome sequences, new theoretical approaches and new experimental techniques, our ability to dissect cellular processes at the molecular level continues to expand. Recent advances include the application of RNA interference methods to characterize loss-of-function ...
Samuel, Karlin   +2 more
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Analysis of the sheep genome

Physiological Genomics, 2001
The identification of genes controlling several traits of interest in sheep has been accomplished by positional candidate cloning. In these studies, the trait is first mapped to a specific chromosomal region by linkage analysis, which requires families that are segregating for the trait and for polymorphic markers.
N E, Cockett, T L, Shay, M, Smit
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Genomic Analysis

2016
Cancer is driven by a plethora of molecular genetic events, including germline alterations that increase individual risk of developing cancer, as well as the somatic aberrations that are selected for in tumor development. As our understanding of these factors increases, it is imperative to translate findings rapidly to the clinic using methodology that
Hunter, Sally M.   +3 more
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Genomic analysis with MapReduce

2015 IEEE International Conference on Big Data (Big Data), 2015
Genomic analysis [1] usually includes a pipeline of three stages: sequence alignment, data conversion, and advanced analysis. The analysis pipeline needs to handle hundreds of gigabytes of data as well as to run complex analytics algorithms, which traditionally takes long execution time (20+ hours) for a full genomes analysis.
Wei-Yi Liu, Hui-I Hsiao, Shih-Yao Dai
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Analysis of parapoxvirus genomes

Archives of Virology, 1985
Eight stomatitis papulosa (SP), four orf and two milker's nodes (MN) virus isolates were compared by restriction enzyme analysis. Considerable genetic heterogeneity was found not only between isolates belonging to the three different taxonomic groups but also between members of the same group.
U, Gassmann, R, Wyler, R, Wittek
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Genomics Analysis: Endometrium

2009
Microarray technology has been used widely in gynecology. Numerous studies have used this method to address biological questions related to human endometrium. The cyclic changes of endometrium confer special characteristics that should be considered before genomic analysis.
Ricardo Francalacci, Savaris   +1 more
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An analysis of sponge genomes

Gene, 2004
The genome of sponges has only been investigated so far by Bartmann-Lindholm et al. [Progr. Colloid. Polym. Sci. 107 (1997) 122-126] who reported a multimodal CsCl profile which could be resolved into five peaks for Geodia cydonium. This problem was reinvestigated here on both G. cydonium and Suberites domuncula.
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Analysis of Genomic DNA with the UCSC Genome Browser

2009
Genomic DNA is being sequenced and annotated at a rapid rate, with terabases of DNA currently deposited in GenBank and other repositories. Genome browsers provide an essential collection of resources to visualize and analyze chromosomal DNA. The University of California, Santa Cruz (UCSC) Genome Browser provides annotations from the level of single ...
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Genomic Southern Blot Analysis

2013
This chapter describes a detailed protocol for genomic Southern blot analysis which can be used to detect transgene or endogenous gene sequences in cereal genomes. The protocol follows a standard approach that has been shown to generate high-quality results: size fractionation of genomic DNA; capillary transfer to a nylon membrane; hybridization with a
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