Results 271 to 280 of about 2,597,991 (390)

The chromosome-level genome assembly and annotation of Salvelinus malma. [PDF]

open access: yesSci Data
Zeng X   +7 more
europepmc   +1 more source

Genome assemblies of osteoglossomorph fish

open access: green, 2016
Peter W. H. Holland, Kyle J. Martin
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

Chromosome-scale genome assembly of B10.RIII, an autoimmune susceptible mouse strain [PDF]

open access: gold
Vijayaraj Nagarajan   +4 more
openalex   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

Chromosome-scale genome assembly of the dune cricket Schizodactylus jimo. [PDF]

open access: yesSci Data
Huang Z   +7 more
europepmc   +1 more source

The genome assembly of asparagus bean, Vigna unguiculata ssp. sesquipedialis [PDF]

open access: gold, 2019
Qiuju Xia   +15 more
openalex   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Chromosome-level genome assembly and annotation of the Triplophysa pappenheimi. [PDF]

open access: yesSci Data
Li Y   +9 more
europepmc   +1 more source

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