Results 161 to 170 of about 1,632,775 (273)

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases [PDF]

open access: green, 2008
Elena Pérez   +22 more
openalex   +1 more source

A Review On Genome Editing

open access: yes, 2017
The Present Review report contains the information about Genome Editing. In this report genome editing is illustrated at the basic level for better understanding. It contains History of Genome Editing from 1800 to Current day i.e. from concept of DNA till current time.
H. P. Suryawanshi   +3 more
openaire   +2 more sources

Heterozygous deletion of 10q24.31-q24.33– a new syndrome associated with multiple congenital anomalies: case report and literature review

open access: yesNeurological Research and Practice
Background Congenital anomalies and neurodevelopmental disorders are complex conditions often requiring comprehensive diagnostic approaches. Next-generation sequencing (NGS), particularly whole-exome sequencing (WES), has greatly improved the detection ...
Anastasiia A. Buianova   +8 more
doaj   +1 more source

Genome Editing of the Octoploid Fragaria x ananassa Using the CRISPR/Cas9 System [PDF]

open access: yes, 2017
Due to its octoploid nature, gene functional analyses in the cultivated strawberry (Fragaria × ananassa) are commonly carried out via gene silencing using self-complementary “hairpin” double-stranded RNA (RNAi) constructs.
Martín-Pizarro, Carmen, Posé, David
core  

Curated loci prime editing (cliPE) for accessible multiplexed assays of variant effect (MAVEs) [PDF]

open access: yesarXiv
Multiplexed assays of variant effect (MAVEs) perform simultaneous characterization of many variants. Prime editing has been recently adopted for introducing many variants in their native genomic contexts. However, robust protocols and standards are limited, preventing widespread uptake. Herein, we describe curated loci prime editing (cliPE) which is an
arxiv  

Increasing Gene Editing Efficiency via CRISPR/Cas9- or Cas12a-Mediated Knock-In in Primary Human T Cells

open access: yesBiomedicines
T lymphocytes represent a promising target for genome editing. They are primarily modified to recognize and kill tumor cells or to withstand HIV infection. In most studies, T cell genome editing is performed using the CRISPR/Cas technology. Although this
Natalia Kruglova, Mikhail Shepelev
doaj   +1 more source

Novel reporter systems for facile evaluation of I-SceI-mediated genome editing [PDF]

open access: gold, 2011
Nina M. Muñoz   +7 more
openalex   +1 more source

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