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Efficient CRISPR-Cas genome editing in brown algae. [PDF]
Cell Rep MethodsMartinho C +7 more
europepmc +1 more source
Correction to 'CasĪ“, an evolutionary transitional CRISPR system enables efficient genome editing across animals and plants'. [PDF]
Nucleic Acids Reseuropepmc +1 more source
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2022
Defined as a condition of body fat excess leading to significant morbidity, obesity is a chronic metabolic illness associated with a significant number of diseases. The incidence of obesity does not solely depend on dietary habits, with energy balance being regulated by the complex interactions between genetic, behavioural and environmental factors ...
Masi D., Tozzi R., Watanabe M.
openaire +3 more sources
Defined as a condition of body fat excess leading to significant morbidity, obesity is a chronic metabolic illness associated with a significant number of diseases. The incidence of obesity does not solely depend on dietary habits, with energy balance being regulated by the complex interactions between genetic, behavioural and environmental factors ...
Masi D., Tozzi R., Watanabe M.
openaire +3 more sources
Current Opinion in Obstetrics & Gynecology, 2023
Purpose of review The development of modern gene editing tools alongside promising innovations in gene sequencing and prenatal diagnostics as well as a shifting regulatory climate around targeted therapeutics offer an opportunity to address monogenic diseases prior to the onset of pathology. In this review, we seek to highlight
Sourav K, Bose +2 more
openaire +2 more sources
Purpose of review The development of modern gene editing tools alongside promising innovations in gene sequencing and prenatal diagnostics as well as a shifting regulatory climate around targeted therapeutics offer an opportunity to address monogenic diseases prior to the onset of pathology. In this review, we seek to highlight
Sourav K, Bose +2 more
openaire +2 more sources
2021
Genome editing has perhaps become the most popular toolbox for generating targeted mutations. Over 0.3% of all publications in PubMed are currently concerned with this topic, demonstrating its importance. Since 2012, there has been an exponential explosion in research articles, owing primarily due to the clustered regulatory interspaced short ...
Henrik U. Stotz, Nobuya Koizuka
+6 more sources
Genome editing has perhaps become the most popular toolbox for generating targeted mutations. Over 0.3% of all publications in PubMed are currently concerned with this topic, demonstrating its importance. Since 2012, there has been an exponential explosion in research articles, owing primarily due to the clustered regulatory interspaced short ...
Henrik U. Stotz, Nobuya Koizuka
+6 more sources
2023
Silkworm is a lepidopteran insect that has been used as a model for a wide variety of biological studies. The microinjection technique is available, and it is possible to cause transgenesis as well as target gene disruption via the genome editing technique. TALEN-mediated knockout is especially effective in this species.
Takuya, Tsubota +2 more
openaire +2 more sources
Silkworm is a lepidopteran insect that has been used as a model for a wide variety of biological studies. The microinjection technique is available, and it is possible to cause transgenesis as well as target gene disruption via the genome editing technique. TALEN-mediated knockout is especially effective in this species.
Takuya, Tsubota +2 more
openaire +2 more sources
Genome editing with retroelements
Science, 2023RNA-guided DNA writing enzymes offer promise for programmable gene ...
Stephen, Tang, Samuel H, Sternberg
openaire +2 more sources