Results 211 to 220 of about 1,457,553 (300)

Correction to "Powering Genome Editing in Rice by Harnessing Promising Gene Resources: A Comprehensive Roadmap". [PDF]

Physiol Plant
europepmc   +1 more source

Compact Cas12f enables genome editing in avian cells. [PDF]

Poult Sci
Han Y, Woo SJ, Choi HJ, Han JY.
europepmc   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Highly frequent undesired insertional mutagenesis during Drosophila genome editing. [PDF]

PLoS Genet
Källstig E, Ruchti E, Raman M, Asadzadeh J, Schneider BL, McCabe BD.   +5 more
europepmc   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Overcoming breeding barriers with genome editing in autopolyploid crops. [PDF]

BMC Plant Biol
Enciso-Rodríguez F, Barrero LS, Garzón-Martínez GA, Kim JH, Kumam Y, Pagliai FA, Jiang T, Huo H, Munoz P.   +8 more
europepmc   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Accurate characterization of CRISPR-Cas9 genome editing outcomes and mosaicism with near-perfect long reads. [PDF]

Genome Med
Höijer I, van Schendel R, Emmanouilidou A, Östlund R, Bunikis I, Tijsterman M, den Hoed M, Ameur A.   +7 more
europepmc   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

Genome Editing in Root and Tuber Crop Development in Sub-Saharan Africa. [PDF]

Plant Environ Interact
Saini H, Kumar R, Manjeet, Banothu S, Reddy SL, Gudihalli Munivenkatappa R, Naik SSS, Kumar R, Pradhan R.   +8 more
europepmc   +1 more source