Results 301 to 310 of about 571,422 (359)

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source

Investigation on ABCC6-Deficient Human Hepatocytes Generated by CRISPR-Cas9 Genome Editing. [PDF]

Cells
Plümers R, Jelinek S, Lindenkamp C, Osterhage MR, Knabbe C, Hendig D.   +5 more
europepmc   +1 more source

An efficient mRNA delivery system for genome editing in plants. [PDF]

Plant Biotechnol J
Qiu F, Xue C, Liu J, Li B, Gao Q, Liang R, Chen K, Gao C.   +7 more
europepmc   +1 more source

Transferable approaches to CRISPR-Cas9 induced genome editing in non-model insects: a brief guide. [PDF]

Front Zool
Ahmed HMM, Zheng L, Hunnekuhl VS.
europepmc   +1 more source

A Strictly Inducible and Orthogonal Dre-rox System for Precise and Markerless Genome Editing in <i>Bacillus subtilis</i>. [PDF]

J Microbiol Biotechnol
Lv J, Fu G, Zhu Q, You W, Guo F, Li R, Zhang D.   +6 more
europepmc   +1 more source

Recent developments, challenges and opportunities in genome editing for crop science from a societal perspective. [PDF]

Front Genome Ed
Venkataraman S, Zaruk D, Hefferon K.
europepmc   +1 more source

Genome Editing in Mouse Embryo Using the CRISPR/Cas12i3 System. [PDF]

Int J Mol Sci
He J, Liu J, Yue Y, Wang L, Liu Z, Xi G, An L, Tian J, Wang Y.   +8 more
europepmc   +1 more source