Results 301 to 310 of about 622,112 (341)
Glycopolymers for Targeted Gene Delivery and Genome Editing
, 2017 Yogesh K. Dhande
openalex +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
2021
Genome editing has perhaps become the most popular toolbox for generating targeted mutations. Over 0.3% of all publications in PubMed are currently concerned with this topic, demonstrating its importance. Since 2012, there has been an exponential explosion in research articles, owing primarily due to the clustered regulatory interspaced short ...
Henrik U. Stotz, Nobuya Koizuka
+8 more sources
Genome editing has perhaps become the most popular toolbox for generating targeted mutations. Over 0.3% of all publications in PubMed are currently concerned with this topic, demonstrating its importance. Since 2012, there has been an exponential explosion in research articles, owing primarily due to the clustered regulatory interspaced short ...
Henrik U. Stotz, Nobuya Koizuka
+8 more sources
Current Opinion in Obstetrics & Gynecology, 2023
Purpose of review The development of modern gene editing tools alongside promising innovations in gene sequencing and prenatal diagnostics as well as a shifting regulatory climate around targeted therapeutics offer an opportunity to address monogenic diseases prior to the onset of pathology. In this review, we seek to highlight
Sourav K, Bose +2 more
openaire +2 more sources
Purpose of review The development of modern gene editing tools alongside promising innovations in gene sequencing and prenatal diagnostics as well as a shifting regulatory climate around targeted therapeutics offer an opportunity to address monogenic diseases prior to the onset of pathology. In this review, we seek to highlight
Sourav K, Bose +2 more
openaire +2 more sources
Therapeutic genome editing: regulatory horizons
Nature Reviews Drug Discovery, 2021An increasing number of genome-editing technologies are being developed. Here, we highlight some of the key issues for future therapies using these technologies from a regulatory perspective.
Hines, Philip A. +4 more
openaire +2 more sources
2023
Targeted editing of the genomes of living organisms not only permits investigations into the understanding of the fundamental basis of biological systems but also allows to improve productively and quality of crops. This includes the creation of plants with valuable compositional properties and with traits that confer resistance to various biotic and ...
openaire +2 more sources
Targeted editing of the genomes of living organisms not only permits investigations into the understanding of the fundamental basis of biological systems but also allows to improve productively and quality of crops. This includes the creation of plants with valuable compositional properties and with traits that confer resistance to various biotic and ...
openaire +2 more sources
2022
Defined as a condition of body fat excess leading to significant morbidity, obesity is a chronic metabolic illness associated with a significant number of diseases. The incidence of obesity does not solely depend on dietary habits, with energy balance being regulated by the complex interactions between genetic, behavioural and environmental factors ...
Masi D., Tozzi R., Watanabe M.
openaire +3 more sources
Defined as a condition of body fat excess leading to significant morbidity, obesity is a chronic metabolic illness associated with a significant number of diseases. The incidence of obesity does not solely depend on dietary habits, with energy balance being regulated by the complex interactions between genetic, behavioural and environmental factors ...
Masi D., Tozzi R., Watanabe M.
openaire +3 more sources
2023
Silkworm is a lepidopteran insect that has been used as a model for a wide variety of biological studies. The microinjection technique is available, and it is possible to cause transgenesis as well as target gene disruption via the genome editing technique. TALEN-mediated knockout is especially effective in this species.
Takuya, Tsubota +2 more
openaire +2 more sources
Silkworm is a lepidopteran insect that has been used as a model for a wide variety of biological studies. The microinjection technique is available, and it is possible to cause transgenesis as well as target gene disruption via the genome editing technique. TALEN-mediated knockout is especially effective in this species.
Takuya, Tsubota +2 more
openaire +2 more sources
2017
Medaka (Oryzias latipes), along with zebrafish (Danio rerio), is a useful experimental model fish. Here, we describe a simple method for generating medaka gene knock-out strains using an automated microchip electrophoresis system. We also describe a method for targeted gene knock-in using a plasmid carrying a sequence that does not cause off-target ...
Satoshi, Ansai, Masato, Kinoshita
openaire +2 more sources
Medaka (Oryzias latipes), along with zebrafish (Danio rerio), is a useful experimental model fish. Here, we describe a simple method for generating medaka gene knock-out strains using an automated microchip electrophoresis system. We also describe a method for targeted gene knock-in using a plasmid carrying a sequence that does not cause off-target ...
Satoshi, Ansai, Masato, Kinoshita
openaire +2 more sources
2018
In the present chapter, we present the protocols and guidelines to facilitate implementation of CRISPR-Cas9 technology in fungi where few or no genetic tools are in place. Hence, we firstly explain how to identify dominant markers for genetic transformation.
Jakob B, Hoof +2 more
openaire +2 more sources
In the present chapter, we present the protocols and guidelines to facilitate implementation of CRISPR-Cas9 technology in fungi where few or no genetic tools are in place. Hence, we firstly explain how to identify dominant markers for genetic transformation.
Jakob B, Hoof +2 more
openaire +2 more sources